Anti-human Sirtuin type 4 (Sirt 4). IgG fraction (monoclonal)

IgG fraction from mouse monoclonal antibody (clone 7C5/E11) obtained by immunization of mice with an ovalbumin-conjugated synthetic peptide corresponding to N-terminal aa1 - aa50 of human silent information regulator 2 homolog (Sirt4). The IgG fraction was purified using Protein G-Sepharose.

• Storage: Store at -20°C.
• Stability: Stable for at least one year. Avoid repeated freezing and thawing.
• Biological activity: This antibody can be used for ELISA assay (1:8,000 dilution). It recognizes Sirt4, a NAD-dependent deacetylase, protein involved in diverse processes ranging from regulation of gene silencing to DNA damage response in mammalian cells.
• Formulation: Solution at 1.0 mg/mL in PBS
• References: Smith, J.S. et al. (2002) Methods Enzymol. 353, 282 - 300.
  Frye, R. (2000) Biochem. Biophys. Res. Commun. 273, 793 - 798.
  Frye, R. (1999) Biochem. Biophys. Res. Commun. 260, 273 - 279.

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