Rabbit anti-Human Heregulin-1 (Neuregulin-1) precursor IgG fraction polyclonal antibody
1mg
$425.00
Skip to product information
Rabbit anti-Human Heregulin-1 (Neuregulin-1) precursor IgG fraction polyclonal antibody
Catalog no.
PN-7070a-9
$425.00
IgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (AGRFSTQEEIQARLSSVIANQDPIAV) corresponding to amino acids 614 - 639 of human Heregulin-1. The IgG fraction was purified using Protein G-Sepharose.
- Storage: Store at -20°C.
- Stability: Stable at least one year at -20°C. Avoid repeated freezing and thawing.
- Biological activity: This polyclonal antibody reacts in ELISA and Western Blot using the immunizing peptide. Heregulin-1, also known as neu differentiation factor -2 (NDF) or Neuregulin-1(NRG1) plays an important role in regulating cell proliferation, metastasis, differentiation, and survival of varios normal and neoplastic tissues. It binds to c-erbB-3 and c-erbB-4 tyrosine kinase receptors, and has diverse functions in neural development and neuromuscular junctions.
- Formulation: Solution at 1 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.
- References: Holmes, W.E. et al. (1992) Science 256, 1205 - 1210. Falls, D.L. (2003) Exp. Cell. Res. 284, 14 - 30. Esper, R.M. et al. (2006) Brain. Res. Rev. 51, 161 - 175.