Anti-human Class II Transactivator (Ciita) IgG fraction (monoclonal)
100 µg
$425.00
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Anti-human Class II Transactivator (Ciita) IgG fraction (monoclonal)
Catalog no.
MA-4031-5
$425.00
IgG fraction from mouse monoclonal antibody (clone 7D3/A1) obtained by immunization of mice with recombinant human CIITA fusion protein. The IgG fraction was purified using Protein G-Sepharose.
- Storage: Store at -20°C.
- Stability: Stable for at least one year. Avoid repeated freezing and thawing
- Biological activity: This antibody can be used in ELISA, Western Blot, and immunoprecipitation. It recognizes CIITA, a non-DNA binding coactivator considered as the master regulator of basal and induced MHC class II specific gene expression. CIITA ensures a tight transcriptional control of these antigen-presenting genes to meet with local requirements for an adequate immune response.
- Formulation: Solution at 1.0 mg/mL in PBS
- References: LeibundGut-Landmann, S. et al. (2004) Eur. J. Immunol. 34, 1513 – 1525; Van den Elsen, P. et al. (2004) Curr. Opin. Immunol. 16, 67 – 75 ; Naves, R. et al. (2002) Int. Immunol. 14, 481 – 491.