Anti-Glycoprotein 1 of Hantaan Virus (HTNV), IgG fraction, Monoclonal, Clone 1F5/G2
100 µg
$499.00
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Anti-Glycoprotein 1 of Hantaan Virus (HTNV), IgG fraction, Monoclonal, Clone 1F5/G2
Catalog no.
HNM-6052AZ1-5
$499.00
Mouse monoclonal antibody IgG fraction (clone 1F5/G2) obtained by immunizing mice with purified recombinant HTNV Glycoprotein 1 µg1). The IgG fraction was purified using Protein G-Sepharose.
- Storage: Store at -20°C.
- Stability: Stable at least one year at -20°C. Avoid repeated freezing and thawing.
- Biological activity: This antibody can be used in ELISA (1:30,000 dilution) and Western blot (1:20,000 dilution) analysis. It recognizes specifically G1 glycoprotein of HTNV. Hantaviruses (family Bunyaviridae) are enveloped viruses that contain a tripartite, negative-stranded RNA genome encoding an RNA-dependent RNA polymerase (L), two integral membrane glycoproteins (G1 and G2), and a nucleocapsid (N) protein. The G1 and G2 glycoproteins form heterodimers and they attach the virion to a cell receptor and to promote fusion membrane after endocytosis of the virion. G1 can dysregulate normal immune and endothelial cell responses and contribute to virus pathogenesis. HTNV is a causative agent of severe hemorrhagic fever mainly in China and it is transmitted by the rodent Apodemus agrarius.
Publications using HNM-6052AZ1
The following scientific publications report use of this Austral Biologicals product:
- Two Point Mutations in Old World Hantavirus Glycoproteins Afford the Generation of Highly Infectious Recombinant Vesicular Stomatitis Virus Vectors. Slough et al., mBio 10(1):e02372-18 (2019).