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HIV-1 Gag p24 Antigen, Recombinant
Catalog no.
HI1A-720-4
$295.00
Protein produced in genetically engineered yeast cells. It covers from Pro 139 to Leu 369 of the HIV-1 gag protein (SF-2 isolate) . It has been purified by ion-exchange chromatography followed by gel filtration.
- Molecular weight: 27 kDa
- Purity: Over 90% pure.
- Storage: Store at -20°C.
- Stability: At least 1 year at -20°C.
- Formulation: Solution at 1 mg/mL in 30mM Tris-HCl, 1mM EDTA (pH 9.0)
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References:
1. Nucleotide sequence and expression of an AIDS,-associated retrovirus (ARV-2). R. Sanchez-Pescador et al. Science 227, 484-492 (1985).
2. Expression of heterologous gene proteins in yeast. S. Pichuantes, A.T. Nguyen and A. Franzusoff. In Protein Engineering: Principles and Practices. J.E. Clealand & C.S. Craik Editors, pp. 129-161 (1996).
Publications using HI1A-720
The following scientific publications report use of Austral Biologicals HIV-1 p24 antigen:
- Autophagy-dependent glutaminolysis drives superior IL21 production in HIV-1-specific CD4 T cells. Loucif et al., Autophagy 18(6):1256-1273 (2022).
- Immunogenicity of a new gorilla adenovirus vaccine candidate for COVID-19. Capone et al., Mol Ther 29(8):2412-2423 (2021).
- Lipophagy confers a key metabolic advantage that ensures protective CD8A T-cell responses against HIV-1. Loucif et al., Autophagy 17(11):3408-3423 (2021).
- Characterization of human immunodeficiency virus type 1 (HIV-1) Gag- and Gag peptide-specific CD4(+) T-cell clones from an HIV-1-seronegative donor following in vitro immunization. Venturini et al., J Virol 76(14):6987-6999 (2002).
- Comparison of human immunodeficiency virus antigens as stimulants for lymphocyte proliferation assays. Schmitz et al., Clin Diagn Lab Immunol 9(3):525-529 (2002).