Human PDGF alpha-receptor extracellular domain (RECOMBINANT)

Human PDGF alpha receptor extracellular domain is produced by genetically engineered Spodoptera frugiperda insect cells (Sf9) infected with recombinant baculovirus, and purified by lectin affinity chromatography.

• Purity: Over 85% pure by SDS gel electrophoresis.
• Storage: Store at -80°C.
• Stability: At least 2 months at -80°C.
• Biological activity: The material is able to bind the ligand (PDGF) as demonstrated by immobilizing the PDGF receptor extracellular domain and establishing competition of binding with radioiodinated PDGF.
• Formulation: 10 mM Tris-HCl, pH 7.0. Concentration: 0.50 mg protein/ml.
• References: 1. Gronwald, R.et al (1988) Proc Natl Acad Sci U S A 85, 3435-39.
  2. Hart, C. E.et al (1988) Science 240, 1529-31.
  3 Tiesman, J., and Hart, C. E. (1993) J Biol Chem 268, 9621-8.
  4. Kelly, J. D.et al. (1991) J Biol Chem 266, 8987-92.

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