Epidermal Growth Factor (EGF), Human Recombinant

Publications using Austral Biologicals EGF

The following scientific publications and protocols report use of EGF supplied by Austral Biologicals:

1. A tissue-engineered human psoriatic skin model: targeting inflammation and glucose metabolism dysregulation in psoriasis using microneedle patches. Ruel et al., Front Mol Biosci (2026).
2. I-TEP: A Simple and Affordable Method to Measure Permeability in Reconstructed Tissues Combined with DAMO-TSC-Based Urea Assay. Sahuc et al., Methods Protoc (2026).
3. Safety aspects of using iodoform as a methane-mitigating feed additive to dairy cows: impacts of milk and serum on bovine mammary and human intestinal epithelial cell lines. Ronn et al., JDS Communications (2026).
4. Airway epithelial stem cell renewal and differentiation: overcoming challenging steps towards clinical-grade tissue engineering. Adamo et al., Stem Cell Res Ther (2025).
5. Correction of Significant Urethral Anomalies Using a Tissue-Engineered Human Urethral Substitute: Proof of Concept. Caneparo et al., Int J Mol Sci (2025).
6. Culture Strategy Determines the Differentiation Status of Sweat Gland Cells. De Koninck et al., Cells (2025).
7. Effect of Fibroblast Growth Factor-2 on Melanocyte Proliferation in Tissue-Engineered Skin Substitutes. Ferland et al., Int J Mol Sci (2025).
8. Isolation and characterization of epithelial cells and fibroblasts from the human penile urethra. Brownell et al., Front Bioeng Biotechnol (2025).
9. Neuronal ALKAL2 and its ALK receptor contribute to the development of colitis-associated colorectal cancer. Delanne-Cuménal et al., Proceedings of the National Academy of Sciences of the United States of America (2025).
10. Antiproliferative and Anti-Inflammatory Effects of the Polyphenols Phloretin and Balsacone C in a Coculture of T Cells and Psoriatic Keratinocytes. Ruel et al., Int J Mol Sci (2024).
11. Cancer Spheroids Embedded in Tissue-Engineered Skin Substitutes: A New Method to Study Tumorigenicity In Vivo. Barbier et al., Int J Mol Sci (2024).
12. Expression and Impact of Fibronectin, Tenascin-C, Osteopontin, and Type XIV Collagen in Fuchs Endothelial Corneal Dystrophy. Tchatchouang et al., Invest Ophthalmol Vis Sci (2024).
13. Influence of Intraocular Pressure on the Expression and Activity of Sodium-Potassium Pumps in the Corneal Endothelium. Anney et al., Int J Mol Sci (2024).
14. MicroRNA-155-5p differentially regulates IL-13Ralpha1 and IL-13Ralpha2 expression and signaling driving abnormal lung epithelial cell phenotype in severe asthma. Klein et al., American Journal of Respiratory Cell and Molecular Biology (2024).
15. Mimicking Urinary Tract Infections Caused by Uropathogenic Escherichia coli Using a Human Three-Dimensional Tissue Engineering Model. Pellerin et al., Microorganisms (2024).
16. Potential of cannabidiol as acne and acne scar treatment: novel insights into molecular pathways of pathophysiological factors. Lee et al., Arch Dermatol Res (2024).
17. Thymic-Epithelial-Cell-Dependent Microenvironment Influences Proliferation and Apoptosis of Leukemic Cells. Patel et al., Int J Mol Sci (2024).
18. A Newly Developed Chemically Defined Serum-Free Medium Suitable for Human Primary Keratinocyte Culture and Tissue Engineering Applications. Ghio et al., Int J Mol Sci (2023).
19. An effective method for culturing functional human corneal endothelial cells using a xenogeneic free culture medium. Alonso-Alonso et al., Sci Rep (2023).
20. Comparison of Two Human Skin Cell Isolation Protocols and Their Influence on Keratinocyte and Fibroblast Culture. Sierra-Sánchez et al., Int J Mol Sci (2023).
21. Heterozygous NF1 dermal fibroblasts modulate exosomal content to promote angiogenesis in a tissue-engineered skin model of neurofibromatosis type-1. Roy et al., Journal of Neurochemistry (2023).
22. In vitro comparison of human plasma-based and self-assembled tissue-engineered skin substitutes: two different manufacturing processes for the treatment of deep and difficult to heal injuries. Sierra-Sánchez et al., Burns Trauma (2023).
23. In vitro glycation of a tissue-engineered wound healing model to mimic diabetic ulcers. Lemarchand et al., Biotechnology and Bioengineering (2023).
24. SARS-CoV-2 infection of thymus induces loss of function that correlates with disease severity. Rosichini et al., J Allergy Clin Immunol (2023).
25. The combination of cigarette smoke and solar rays causes effects similar to skin aging in a bilayer skin model. Grenier et al., Sci Rep (2023).
26. Alpha-Linolenic Acid Modulates T Cell Incorporation in a 3D Tissue-Engineered Psoriatic Skin Model. Morin et al., Cells (2022).
27. Antipsoriatic Potential of Quebecol and Its Derivatives. Bouchard et al., Pharmaceutics (2022).
28. Bisphenols A and S Alter the Bioenergetics and Behaviours of Normal Urothelial and Bladder Cancer Cells. Pellerin et al., Cancers (Basel) (2022).
29. Cancer-Associated Fibroblasts in a 3D Engineered Tissue Model Induce Tumor-like Matrix Stiffening and EMT Transition. Millet et al., Cancers (Basel) (2022).
30. Efficient Gamma-Retroviral Transduction of Primary Human Skin Cells Using the EF-c Peptide as a Transduction Enhancer. Barbier et al., Current Protocols (2022).
31. Engineered human organ-specific urethra as a functional substitute. Caneparo et al., Sci Rep (2022).
32. Evaluation of a Serum-Free Medium for Human Epithelial and Stromal Cell Culture. Caneparo et al., Int J Mol Sci (2022).
33. Gene Profiling of a 3D Psoriatic Skin Model Enriched in T Cells: Downregulation of PTPRM Promotes Keratinocyte Proliferation through Excessive ERK1/2 Signaling. Rioux et al., Cells (2022).
34. Glucuronidated Metabolites of Bisphenols A and S Alter the Properties of Normal Urothelial and Bladder Cancer Cells. Pellerin et al., Int J Mol Sci (2022).
35. Isolation efficiency of collagenase and EDTA for the culture of corneal endothelial cells. Santerre et al., Mol Vis (2022).
36. Personalized Scaffolds for Diabetic Foot Ulcer Healing Using Extracellular Matrix from Induced Pluripotent Stem-Reprogrammed Patient Cells. Santarella et al., Adv Nanobiomed Res (2022).
37. Protease-activated receptor-2 activation enhances epithelial wound healing via epidermal growth factor receptor. Bandara et al., Tissue Barriers (2022).
38. TGF-β-Mediated Modulation of Cell-Cell Interactions in Postconfluent Maturing Corneal Endothelial Cells. Santerre et al., Invest Ophthalmol Vis Sci (2022).
39. Tie-Over Bolster Pressure Dressing Improves Outcomes of Skin Substitutes Xenografts on Athymic Mice. Cartier et al., Int J Mol Sci (2022).
40. Antioxidant, Anti-Inflammatory, and Anti-Aging Potential of a Kalmia angustifolia Extract and Identification of Some Major Compounds. Grenier et al., Antioxidants (Basel) (2021).
41. Bisphenol A Alters the Energy Metabolism of Stromal Cells and Could Promote Bladder Cancer Progression. Pellerin et al., Cancers (Basel) (2021).
42. Differential Marker Expression between Keratinocyte Stem Cells and Their Progeny Generated from a Single Colony. Ali et al., Int J Mol Sci (2021).
43. Polyvinyl alcohol increased growth, migration, invasion, and sphere size in the PK-8 pancreatic ductal adenocarcinoma cell line. Gomi et al., Heliyon (2021).
44. The Whitening Properties of the Mixture Composed of Pomegranate, Osmanthus and Olive and the Protective Effects Against Ultraviolet Deleterious Effects. Wang et al., Clin Cosmet Investig Dermatol (2021).
45. FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer. Sasaki et al., Cancers (Basel) (2020).
46. Reduced graphene oxide membranes in ocular regenerative medicine. Zambrano-Andazol et al., Materials Science and Engineering C (2020).
47. Biological Assessment of Zn-Based Absorbable Metals for Ureteral Stent Applications. Paramitha et al., Materials (Basel) (2019).
48. Differentiation of diabetic foot ulcer-derived induced pluripotent stem cells reveals distinct cellular and tissue phenotypes. Kashpur et al., FASEB J (2019).
49. Dihydrochalcone Derivatives from Populus balsamifera L. Buds for the Treatment of Psoriasis. Bélanger et al., Int J Mol Sci (2019).
50. Effect of food ingredients on glucagon-like peptide-1 secretion in STC-1 and HuTu-80 cells. Yue et al., International Journal of Food Science & Technology (2019).
51. Ganglioside GM2, highly expressed in the MIA PaCa-2 pancreatic ductal adenocarcinoma cell line, is correlated with growth, invasion, and advanced stage. Sasaki et al., Sci Rep (2019).
52. Generation of High-Titer Self-Inactivated γ-Retroviral Vector Producer Cells. Ghani et al., Mol Ther Methods Clin Dev (2019).
53. Grafting of an autologous tissue-engineered human corneal epithelium to a patient with limbal stem cell deficiency (LSCD). Le-Bel et al., Am J Ophthalmol Case Rep (2019).
54. Laminin 332-Dependent YAP Dysregulation Depletes Epidermal Stem Cells in Junctional Epidermolysis Bullosa. De Rosa et al., Cell Reports (2019).
55. Modulation of the Lipid Profile of Reconstructed Skin Substitutes after Essential Fatty Acid Supplementation Affects Testosterone Permeability. Simard et al., Cells (2019).
56. Selective Ah Receptor Ligands Mediate Enhanced SREBP1 Proteolysis to Restrict Lipogenesis in Sebocytes. Muku et al., Toxicol Sci (2019).
57. Targeted inactivation of EPS8 using dendrimer-mediated delivery of RNA interference. Yuan et al., Int J Pharm (2019).
58. Vitrification and storage of oral mucosa epithelial cell sheets. Oliva et al., J Tissue Eng Regen Med (2019).
59. An efficient in vitro transposition method by a transcriptionally regulated Sleeping Beauty system packaged into an integration defective lentiviral vector. Benati et al., Journal of Visualized Experiments (2018).
60. Are the Effects of the Cholera Toxin and Isoproterenol on Human Keratinocytes' Proliferative Potential Dependent on Whether They Are Co-Cultured with Human or Murine Fibroblast Feeder Layers?. Cortez Ghio et al., Int J Mol Sci (2018).
61. Characterization of Epidermal Lipoxygenase Expression in Normal Human Skin and Tissue-Engineered Skin Substitutes. Simard-Bisson et al., J Histochem Cytochem (2018).
62. Extracellular Matrix and Integrin Expression Profiles in Fuchs Endothelial Corneal Dystrophy Cells and Tissue Model. Goyer et al., Tissue Eng Part A (2018).
63. First-in-human application of the self-assembled skin substitute as permanent graft to treat burn patients: a case series of 14 patients indicating clinical effectiveness. Germain et al., Cytotherapy (2018). Conference abstract
64. Natural Substances for Prevention of Skin Photoaging: Screening Systems in the Development of Sunscreen and Rejuvenation Cosmetics. Kostyuk et al., Rejuvenation Res (2018).
65. Platycodin D May Improve Acne and Prevent Scarring by Downregulating SREBP-1 Expression Via Inhibition of IGF-1R/PI3K/Akt Pathway and Modulating Inflammation with an Increase in Collagen. Suh et al., Ann Dermatol (2018).
66. Specialized Living Wound Dressing Based on the Self-Assembly Approach of Tissue Engineering. Cantin-Warren et al., J Funct Biomater (2018).
67. TGF-β1 promotes cell barrier function upon maturation of corneal endothelial cells. Beaulieu Leclerc et al., Sci Rep (2018).
68. The Tissue-Engineered Human Psoriatic Skin Substitute: A Valuable In Vitro Model to Identify Genes with Altered Expression in Lesional Psoriasis. Rioux et al., Int J Mol Sci (2018).
69. Tissue-engineered 3D melanoma model with blood and lymphatic capillaries for drug development. Bourland et al., Sci Rep (2018).
70. Expression of C4.4A in an In Vitro Human Tissue-Engineered Skin Model. Jacobsen et al., Biomed Res Int (2017).
71. A 3D-psoriatic skin model for dermatological testing: The impact of culture conditions. Duque-Fernandez et al., Biochem Biophys Rep (2016).
72. Effect of connexin 43 inhibition by the mimetic peptide Gap27 on corneal wound healing, inflammation and neovascularization. Elbadawy et al., Br J Pharmacol (2016).
73. Generation of Induced Pluripotent Stem Cells from Diabetic Foot Ulcer Fibroblasts Using a Nonintegrative Sendai Virus. Gerami-Naini et al., Cell Reprogram (2016).
74. Human Bone Derived Collagen for the Development of an Artificial Corneal Endothelial Graft. In Vivo Results in a Rabbit Model. Vázquez et al., PLoS One (2016).
75. Improved methods to produce tissue-engineered skin substitutes suitable for the permanent closure of full-thickness skin injuries. Larouche et al., BioResearch Open Access (2016).
76. In Vivo Functionality of a Corneal Endothelium Transplanted by Cell-Injection Therapy in a Feline Model. Bostan et al., Invest Ophthalmol Vis Sci (2016).
77. Origin of Serum Affects Quality of Engineered Tissues Produced by the Self-Assembly Approach. Chabaud et al., Scientifica (Cairo) (2016).
78. Amniotic Membrane Modifies the Genetic Program Induced by TGFß, Stimulating Keratinocyte Proliferation and Migration in Chronic Wounds. Alcaraz et al., PLoS One (2015).
79. Demonstration of the direct impact of ketamine on urothelium using a tissue engineered bladder model. Bureau et al., Can Urol Assoc J (2015).
80. Early detection of structural abnormalities and cytoplasmic accumulation of TDP-43 in tissue-engineered skins derived from ALS patients. Paré et al., Acta Neuropathol Commun (2015).
81. High yield extraction of pure spinal motor neurons, astrocytes and microglia from single embryo and adult mouse spinal cord. Beaudet et al., Sci Rep (2015).
82. Optimization of the current self-assembled urinary bladder model: Organ-specific stroma and smooth muscle inclusion. Orabi et al., Can Urol Assoc J (2015).
83. Picea mariana polyphenolic extract inhibits phlogogenic mediators produced by TNF-alpha-activated psoriatic keratinocytes: impact on NF-kappaB pathway. Garcia-Perez et al., Journal of Ethnopharmacology (2014).
84. Sensory neurons accelerate skin reepithelialization via substance P in an innervated tissue-engineered wound healing model. Blais et al., Tissue Eng Part A (2014).
85. An endothelialized urothelial cell-seeded tubular graft for urethral replacement. Imbeault et al., Can Urol Assoc J (2013).
86. High throughput kinase inhibitor screens reveal TRB3 and MAPK-ERK/TGFβ pathways as fundamental Notch regulators in breast cancer. Izrailit et al., Proc Natl Acad Sci U S A (2013).
87. Irradiated human dermal fibroblasts are as efficient as mouse fibroblasts as a feeder layer to improve human epidermal cell culture lifespan. Bisson et al., Int J Mol Sci (2013).
88. Keratinocytes and head and neck squamous cell carcinoma cells regulate urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in fibroblasts. Hakelius et al., Anticancer Research (2013).
89. Optimization of the porcine adult skin-derived precursor cell isolation protocol. Iribar et al., Stem Cell Discovery (2013).
90. TGFβ signaling regulates lipogenesis in human sebaceous glands cells. McNairn et al., BMC Dermatol (2013).
91. Anti-inflammatory effects of concentrated ethanol extracts of Edelweiss (Leontopodium alpinum Cass.) callus cultures towards human keratinocytes and endothelial cells. Daniela et al., Mediators Inflamm (2012).
92. Bi-layered collagen nano-structured membrane prototype (collagen matrix 10826) for oral soft tissue regeneration: an in vitro study. Nocini et al., Clinical Oral Implants Research (2012).
93. Enhanced expression of fibroblast growth factor receptor 2 IIIc promotes human pancreatic cancer cell proliferation. Ishiwata et al., Am J Pathol (2012).
94. Use of autologous skin equivalents with artificial dermal matrix (Integra) in donor site coverage in radial forearm free flaps: preliminary cases. Pena et al., Journal of Oral and Maxillofacial Surgery (2012).
95. Anti-tumour activity of afatinib, an irreversible ErbB family blocker, in human pancreatic tumour cells. Ioannou et al., Br J Cancer (2011).
96. Epstein-Barr virus LMP1 activates EGFR, STAT3, and ERK through effects on PKCdelta. Kung et al., J Virol (2011).
97. Morphological and cytoskeletal alterations of nervous system tumor cells with different culturing methods. Matsuda et al., International Journal of Oncology (2011).
98. Analysis of ligand-receptor interaction on the surface of living cells by fluorescence correlation spectroscopy. Miyagi et al., The Open Spectroscopy Journal (2010).
99. Dendrimer-triglycine-EGF nanoparticles for tumor imaging and targeted nucleic acid and drug delivery. Yuan et al., Oral Oncol (2010).
100. EPS8 upregulates FOXM1 expression, enhancing cell growth and motility. Wang et al., Carcinogenesis (2010).
101. Evaluation of tumorigenic risk of tissue-engineered oral mucosal epithelial cells by using combinational examinations. Thepot et al., Cell Transplantation (2010).
102. Three-dimensional human tissue models of wounded skin. Egles et al., Methods Mol Biol (2010).
103. Cultivo in vitro con colageno y fibroblastos humanos de un equivalente de mucosa oral de espesor total. Gonzalez Mendez et al., Revista Espanola de Cirugia Oral y Maxilofacial (2009).
104. Differential effects of falcarinol and related aliphatic C(17)-polyacetylenes on intestinal cell proliferation. Purup et al., J Agric Food Chem (2009).
105. Escherichia coli expression and refolding of E/K-coil-tagged EGF generates fully bioactive EGF for diverse applications. Le et al., Protein Expression and Purification (2009).
106. Innate immune responses of airway epithelium to house dust mite are mediated through beta-glucan-dependent pathways. Nathan et al., J Allergy Clin Immunol (2009).
107. Regeneration of skin and cornea by tissue engineering. Larouche et al., Methods in Molecular Biology (2009).
108. Role for EPS8 in squamous carcinogenesis. Wang et al., Carcinogenesis (2009).
109. Toward effective HIV vaccination: induction of binary epitope reactive antibodies with broad HIV neutralizing activity. Nishiyama et al., J Biol Chem (2009).
110. Characterization of wound reepithelialization using a new human tissue-engineered corneal wound healing model. Carrier et al., Investigative Ophthalmology & Visual Science (2008).
111. Differential sensitivity of A549 non-small lung carcinoma cell responses to epidermal growth factor receptor pathway inhibitors. Jaramillo et al., Cancer Biology & Therapy (2008).
112. Keratin down-regulation in vimentin-positive cancer cells is reversible by vimentin RNA interference, which inhibits growth and motility. Paccione et al., Molecular Cancer Therapeutics (2008).
113. Three-dimensional tissue models of normal and diseased skin. Carlson et al., Curr Protoc Cell Biol (2008).
114. Optimization of culture conditions for porcine corneal endothelial cells. Proulx et al., Mol Vis (2007).
115. TGF-beta suppresses EGF-induced MAPK signaling and proliferation in asthmatic epithelial cells. Semlali et al., American Journal of Respiratory Cell and Molecular Biology (2007).
116. Autologous transplantation of rabbit limbal epithelia cultured on fibrin gels for ocular surface reconstruction. Talbot et al., Molecular Vision (2006).
117. Down-regulation of CXCL5 inhibits squamous carcinogenesis. Miyazaki et al., Cancer Research (2006).
118. Effect of the anti-receptor ligand-blocking 225 monoclonal antibody on EGF receptor endocytosis and sorting. Jaramillo et al., Experimental Cell Research (2006).
119. In vitro three-dimensional reconstruction of human bladder mucosa. de Diego Rodriguez et al., Actas Urologicas Espanolas (2006).
120. Inhibition of transendothelial migration and invasion of human breast cancer cells by preventing geranylgeranylation of Rho. Kusama et al., International Journal of Oncology (2006).
121. Pancreatic duct epithelial cell isolation and cultivation in two-dimensional and three-dimensional culture systems. Agbunag et al., Methods in Enzymology (2006).
122. Tissue inhibitor of metalloproteinase-2 (TIMP-2) expression is regulated by multiple neural differentiation signals. Jaworski et al., J Neurochem (2006).
123. Dynamic changes in nicotinamide pyridine dinucleotide content in normal human epidermal keratinocytes and their effect on retinoic acid biosynthesis. Pinkas-Sarafova et al., Biochemical and Biophysical Research Communications (2005).
124. Ectodomain shedding of the hypoxia-induced carbonic anhydrase IX is a metalloprotease-dependent process regulated by TACE/ADAM17. Zatovicova et al., Br J Cancer (2005).
125. Effect of polycyclic aromatic hydrocarbons on generation and efflux of glutathione conjugates in primary cultured alveolar epithelial cells. Nagayoshi et al., Drug Metabolism and Pharmacokinetics (2004).
126. Experimental study about viability of autologous free graft in vitro cultivated urinary epithelium. de Diego Rodriguez et al., Actas Urologicas Espanolas (2004).
127. Investigation of three new mouse mammary tumor cell lines as models for transforming growth factor (TGF)-beta and Neu pathway signaling studies: identification of a novel model for TGF-beta-induced epithelial-to-mesenchymal transition. Lenferink et al., Breast Cancer Res (2004).
128. Thymic epithelial cells promote survival of human T-cell acute lymphoblastic leukemia blasts: the role of interleukin-7. Scupoli et al., Haematologica (2003).
129. 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis. Kusama et al., Gastroenterology (2002).
130. Signaling disrupts mSin3A binding to the Mad1-like Sin3-interacting domain of TIEG2, an Sp1-like repressor. Ellenrieder et al., EMBO J (2002).
131. Differential effects of retinoids on proliferation of bovine mammary epithelial cells in collagen gel culture. Purup et al., Journal of Dairy Research (2001).
132. Epidermal growth factor regulation of rat NHE2 gene expression. Xu et al., American Journal of Physiology-Cell Physiology (2001).
133. Feline head and neck squamous cell carcinoma cell line: characterization, production of parathyroid hormone-related protein, and regulation by transforming growth factor-beta. Tannehill-Gregg et al., In Vitro Cellular & Developmental Biology - Animal (2001).
134. Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. Kusama et al., Cancer Research (2001).
135. Porcine small intestinal submucosa (SIS): a bioscaffold supporting in vitro primary human epidermal cell differentiation and synthesis of basement membrane proteins. Lindberg et al., Burns (2001).
136. Regulation of neuregulin expression in the injured rat brain and cultured astrocytes. Tokita et al., J Neurosci (2001).
137. Bacterial colonization and healing of gastric ulcers: the effects of epidermal growth factor. Elliott et al., American Journal of Physiology-Gastrointestinal and Liver Physiology (2000).
138. Differential regulation of insulin-like growth factor-binding protein-3 protease activity in MCF-7 breast cancer cells by estrogen and transforming growth factor-beta1. Salahifar et al., Endocrinology (2000).
139. Keratinocytes influence the maturation and organization of the elastin network in a skin equivalent. Duplan-Perrat et al., Journal of Investigative Dermatology (2000).
140. Effects of orally administered epidermal growth factor on enteropathogenic Escherichia coli infection in rabbits. Buret et al., Infect Immun (1998).
141. Insulin-related growth factors stimulate proliferation of retinal progenitors in the goldfish. Boucher et al., Journal of Comparative Neurology (1998).
142. Thymocyte contact or monoclonal antibody-mediated clustering of alpha3beta1 or alpha6beta4 integrins activate interleukin-6 transcription factors and IL-6 production in human thymic epithelial cells. Ramarli et al., Blood (1998).
143. Nerve growth factor binds to normal human keratinocytes through high and low affinity receptors and stimulates their growth by a novel autocrine loop. Di Marco et al., Journal of Biological Chemistry (1993).