Interleukin-6 (IL-6), Human Recombinant
25 µg
$250.00
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Interleukin-6 (IL-6), Human Recombinant
Catalog no.
CI-460-33
$250.00
Human Interleukin-6 (IL-6) plays a role in the mediation of the inflammatory and immune response initiated by infection or injury. IL-6 acts on B cells by stimulating differentiation and antibody secretion. IL-6 also exhibits growth factor activity for mature thymic or peripheral T cells, and enhances the differentiation of cytotoxic T cells in the presence of IL-2 or IFNt. This glycoprotein is composed of 184 amino acid residues, and has a 42% homology with murine IL-6. Human Interleukin-6 (RECOMBINANT) is produced in genetically engineered Spodoptera frugiperda insect cells (Sf9) infected with recombinant viruses, and purified by sequential chromatography.
- Molecular weight: 20-21 kDa (glycoprotein)
- Purity: Over 85% pure by SDS gel electrophoresis. There is < 1ng/mg endotoxin.
- Storage: Store at -80°C.
- Stability: At least 1 year at -80°C.
- Biological activity: 3H-thymidine uptake by B9 murine thymoma cell line that is IL-6 dependent.
- Formulation: Frozen liquid solution (PBS) at 0.50 mg/mL (50 µL/vial)
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References:
1. Taga, T., and Kishimoto, T., (1997) Ann. Rev. Immunology, 15, 797-819