Skip to product information
IGF-Binding Protein 6, Human Recombinant
Catalog no.
BP-380-2
$275.00
Human IGF-Binding protein 6 is produced in genetically engineered yeast, and purified by affinity chromatography and HPLC.
- Molecular weight: 24 kDa
- Purity: Over 90% pure by SDS gel electrophoresis.
- Storage: Store at +4°C. Reconstitution is best in water or buffer near neutral pH. After reconstitution, storage in aliquots at -80°C is recommended.
- Stability: Several months at +4°C.
- Biological activity: Binding activity of human IGF-BP 6 is determined by the inhibition activity of both IGF I and II.
- Formulation: Lyophilized powder
-
References:
1.Kiefer, M.C., Schmid, C., Waldvogel, M., Sclapfer, I., Futo, E., Maziarz, F.R., Green, K., Barr, P.J. and Zapf, J. (1992) The Journal of Biological Chemistry, Vol 267, No 18, 12692-12699
2. Rechler M.M. and Brown A.L. (1992) Growth Regulation, 2, 55.
3. Modern Concepts of Insulin-Like Growth Factor. Ed. E. Martin Spencer, M.D. (1991). Elsevier Science Publ., pages 311-415
Publications using BP-380
The following scientific publication report use of this Austral Biologicals product:
- Interactions of high affinity insulin-like growth factor-binding proteins with the type V transforming growth factor-beta receptor in mink lung epithelial cells. Leal et al., J Biol Chem 274(10):6711-6717 (1999).