{"product_id":"tp-2001","title":"Rabbit anti-Human Upstream Stimulatory Factor 1 (USF1) IgG fraction polyclonal antibody","description":"\u003cp\u003eIgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (MKGQQKTAETEEGT) corresponding to amino acids 1-14 of human USF-1. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable at least one year at -20°C. Avoid repeated freezing and thawing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This polyclonal antibody can be used in ELISA (1: 250 dilution), immunocytochemistry (1: 100 dilution) and it recognizes USF-1 (33,5 kDa) in Western blot of HeLa lysate (1: 500 dilution). Upstream stimulatory factor 1 (UFS-1) is a 33.5 kDa nuclear protein that exhibits site-specific DNA binding activating the transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. USF-1 is a member of the basic helix-loop-helix leucine zipper family and can function as a cellular transcription factor.This protein has been associated to familial combined hyperlipidemia.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1 mg\/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Sawadogo, M. (1988) J. Biol. Chem. 263, 11994-12001. Gregor, P.D. et al. (1990) Genes Dev. 4, 1730-1740. Pajukanta, P. et al. (2004) Nat. Genet. 36, 371-376.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_TP-2001_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"1mg","offer_id":52517560221998,"sku":"TP-2001-9","price":425.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-tp-2001-1mg.png?v=1788007795","url":"https:\/\/www.australbiologicals.com\/products\/tp-2001","provider":"Austral Biologicals","version":"1.0","type":"link"}