{"product_id":"pn-7030a","title":"Rabbit anti-Human Alpha, Beta and Gamma- Synuclein IgG fraction polyclonal antibody","description":"\u003cp\u003eIgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (AKEGVVAAEKTKQGV) corresponding to amino acids 11 - 26 of human alpha, beta and gamma-synuclein. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable at least one year at -20°C. Avoid repeated freezing and thawing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This polyclonal antibody reacts in ELISA and Western Blot using the immunizing peptide. The synucleins (alpha, beta and gamma) are a family of soluble presynaptic proteins expressed in neural tissue. Synucleins are thought to be involved in neuronal plasticity, synaptic function, and neurodegenerative diseases. Gamma-synuclein is abnormally expressed in tumor tissues of different cancers.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1 mg\/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Clayton, D.F. \u0026amp; George, J.M. (1998) Trends Neurosci. 21 (6), 249 254. Lavedan, C. (1998) Genome Res. 8, 871 - 880. George, J.M.(2002) Genome Biol.3, 3002.1 - 3002.6\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_PN-7030A_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"1mg","offer_id":52517555175726,"sku":"PN-7030a-9","price":425.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-pn-7030a-1mg.png?v=1788008140","url":"https:\/\/www.australbiologicals.com\/products\/pn-7030a","provider":"Austral Biologicals","version":"1.0","type":"link"}