{"product_id":"pn-7000a","title":"Rabbit anti-Human Alpha- Synuclein IgG fraction polyclonal antibody","description":"\u003cp\u003eIgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (PQEGILEDMPVDP) corresponding to amino acids 108 - 120 of human Alpha-Synuclein. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable at least one year at -20°C. Avoid repeated freezing and thawing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This polyclonal antibody reacts in ELISA using immunizing peptide. Human Alpha Synuclein is a soluble protein highly abundant in presynaptic nerve terminals and a member of the synuclein family. It can form filamentous aggregates that are the major non-amyloid components of intracellular inclusions in several neurodegenerative diseases such as Alzheimer and Parkinson.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1 mg\/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Clayton, D.F. \u0026amp; George, J.M. (1998) Trends Neurosci. 21 (6), 249 254.Goldberg, M.S. \u0026amp; Lansbury Jr., P.T. (2000) Nat. Cell Biol. 2, 115 - 119.George, J.M. (2002) Genome Biol.3, 3002.1 - 3002.6. Alves da Costa, C. (2003) Curr. Mol. Med. 3, 17 - 24.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_PN-7000A_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"1mg","offer_id":52517555044654,"sku":"PN-7000a-9","price":425.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-pn-7000a-1mg.png?v=1788008141","url":"https:\/\/www.australbiologicals.com\/products\/pn-7000a","provider":"Austral Biologicals","version":"1.0","type":"link"}