{"product_id":"mr-951","title":"Anti-hTNF Receptor-Associated Factor 2 (TRAF 2). IgG faction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 2I10\/I5) obtained by immunization of mice with human TRAF2 (50 kDa). The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used for ELISA assay (1:2,000 dilution). TRAF2 is a signal transducer protein that associates with the cytoplasmic domain of TNF receptor to different signaling pathways. It regulates two distinct kinase cascades which lead to NF-?B and JUNK activation. It is also involved in anti-apoptotic signaling, perinatal survival and IL-15 signaling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1.0 mg\/mL in PBS.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Chung, Y.J. et al. (2002) J. Cell. Sci. 115, 679 - 688.\u003cbr\u003eBradley, J.R. \u0026amp; Pober, J. (2001) Oncogene 20, 6482 - 6491.\u003cbr\u003eWajant, H. et al. (2001) Cell. Signal. 13, 389 - 400.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MR-951_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"50 µg","offer_id":52518883295534,"sku":"MR-951-4","price":275.0,"currency_code":"USD","in_stock":true},{"title":"250 µg","offer_id":52518883328302,"sku":"MR-951-7","price":400.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-mr-951-50ug.png?v=1788008244","url":"https:\/\/www.australbiologicals.com\/products\/mr-951","provider":"Austral Biologicals","version":"1.0","type":"link"}