{"product_id":"mr-851","title":"Anti-human Vascular Endothelial Growth Factor receptor 1 (VEGFR-1 or FLT-1) IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 6D1\/G11) obtained by immunization of mice with the extracellular domain of human VEGFR-1 (106 kDa). The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in ELISA assays (1: 8,000 dilution). It recognizes the extracellular domain of human VEGFR-1, a type I membrane protein. This protein binds VEGF, PLGF and VEGFB and belongs to the tyrosine protein kinase family. The VEGFR-1 has a signaling role in mediating monocyte chemotaxis in tumor disease and performs an inhibitory role by sequestering VEGF and preventing its interaction with VEGFR-2\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1.0 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Ferrara, N. et al. (2003) Nat. Med. 9, 669 – 676; Cross, M.J. et al. (2003) Trends Biochem. Sci. 28, 488 – 494.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MR-851_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"50 µg","offer_id":52518883229998,"sku":"MR-851-4","price":275.0,"currency_code":"USD","in_stock":true},{"title":"250 µg","offer_id":52518883262766,"sku":"MR-851-7","price":400.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-mr-851-50ug.png?v=1788008262","url":"https:\/\/www.australbiologicals.com\/products\/mr-851","provider":"Austral Biologicals","version":"1.0","type":"link"}