{"product_id":"mr-421b","title":"Anti-Interleukin-2 Receptor Beta chain (Il-2R) extracellular domain (CD122). IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 6B9\/F11) obtained by immunization of mice with the extra-cellular domain of interleukin 2 receptor beta chain (32 kDa). The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used for ELISA assay (1:2,000 dilution). The IL-2R beta chain (CD122) associates with CD25 (IL-2R a chain), and CD132 (? chain of IL-2, IL-4, IL-7, IL-9, IL-13, IL-15 receptors) to form the high-affinity IL-2 receptor. It is critical for mediating biological effects of IL-2 and IL-15 on T cells and NK cells.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 0.5 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Minami, Y. et al. (1993) Ann. Rev. Immunol. 11, 245 - 268\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MR-421B_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"50 µg","offer_id":52518882672942,"sku":"MR-421B-4","price":275.0,"currency_code":"USD","in_stock":true},{"title":"250 µg","offer_id":52518882705710,"sku":"MR-421B-7","price":400.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-mr-421b-50ug.png?v=1788008262","url":"https:\/\/www.australbiologicals.com\/products\/mr-421b","provider":"Austral Biologicals","version":"1.0","type":"link"}