{"product_id":"ma-cd8","title":"Anti-human T-Cell Surface Glycoprotein CD8. IgG fraction (Monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 1C8\/D8) obtained by immunization of mice with human CD8+ T- lymphocyte. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used for ELISA assay. Human CD8 is expressed either as an aß heterodimer or an aa homodimer by the cytotoxic\/suppressor subset of T-cells and weakly by NK cells. CD8 acts as co-receptor in class I MHC-restricted antigen-induced T cell activation (binds to class I MHC molecules). It also participates in the thymocyte development.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 0.5 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Ellmeier, W. el. al. (1999) Annu, Rev. Immunol. 17, 523 - 554.\u003cbr\u003eLittman, D.R. et al. (1985) Cell 40, 237 - 246.\u003cbr\u003ePerussia, B. et al. (1983) J. Immunol. 131, 223 - 231.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD8_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881689902,"sku":"MA-CD8-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd8-200ug.png?v=1788008296","url":"https:\/\/www.australbiologicals.com\/products\/ma-cd8","provider":"Austral Biologicals","version":"1.0","type":"link"}