Anti-human T-Cell Surface Glycoprotein CD8. IgG fraction (Monoclonal)
200 µg
$275.00
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Anti-human T-Cell Surface Glycoprotein CD8. IgG fraction (Monoclonal)
Catalog no.
MA-CD8-6
$275.00
IgG fraction from mouse monoclonal antibody (clone 1C8/D8) obtained by immunization of mice with human CD8+ T- lymphocyte. The IgG fraction was purified using Protein G-Sepharose.
- Biological activity: This antibody can be used for ELISA assay. Human CD8 is expressed either as an aß heterodimer or an aa homodimer by the cytotoxic/suppressor subset of T-cells and weakly by NK cells. CD8 acts as co-receptor in class I MHC-restricted antigen-induced T cell activation (binds to class I MHC molecules). It also participates in the thymocyte development.
- Formulation: Solution at 0.5 mg/mL in PBS
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References: Ellmeier, W. el. al. (1999) Annu, Rev. Immunol. 17, 523 - 554.
Littman, D.R. et al. (1985) Cell 40, 237 - 246.
Perussia, B. et al. (1983) J. Immunol. 131, 223 - 231.