{"product_id":"ma-cd58","title":"Anti-human Lymphocyte Function Associated Antigen 3 (LFA-3); CD58 IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 2B2\/D3) obtained by immunization of mice with human T lymphocytes. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in immunoprecipitation, and flow cytometry, it also inhibits the cytolytic T lymphocyte (CTL) activity. It recognizes CD58 (also known as LFA-3), a 60-70 kDa membrane glycoprotein member of the immunoglobulin super family. CD58 is expressed on haemopoetic cells and it functions as an adhesion molecule mediating a co-stimulatory signal through CD2.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1.0 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e van der Merwe, P.A. \u0026amp; Davis, S.J. (2003) Annu. Rev. Immunol. 21, 659 – 684; Wang, J-H. et al. (1999) Cell 97, 791 – 803; Wallner, B.P. et al. (1987) J. Exp. Med. 166, 923 – 932.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD58_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881657134,"sku":"MA-CD58-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd58-200ug.png?v=1788008295","url":"https:\/\/www.australbiologicals.com\/products\/ma-cd58","provider":"Austral Biologicals","version":"1.0","type":"link"}