Anti-human CD45 (Leukocyte Common Antigen) IgG fraction (monoclonal)
200 µg
$275.00
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Anti-human CD45 (Leukocyte Common Antigen) IgG fraction (monoclonal)
Catalog no.
MA-CD45-6
$275.00
IgG fraction from mouse monoclonal antibody (clone 8G3/A1) obtained by immunization of mice with human lymphocytes. The IgG fraction was purified using Protein G-Sepharose.
- Storage: Store at -20°C.
- Stability: Stable for at least one year. Avoid repeated freezing and thawing
- Biological activity: This antibody can be used in flow cytometry studies. It recognizes all isoforms of the CD45 (LCA). CD45 is a transmembrane tyrosine phosphatase, expressed on nucleated hematopoitic cells, which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing. CD45 functions as a leukocyte membrane receptor signal transduction. It plays an essential role in the regulation of leukocyte activation, development, and function.
- Formulation: Solution at 1.0 mg/mL in PBS
- References: Mustelin, T. et al. (2004) Mol. Immunol. 41, 687 – 700 ; Trowbridge, I.S. et al. (1994) Annu. Rev. Immunol. 12, 85 – 116 ; Justement, L.B. et al. (1991) Science 252, 1839 – 1842.