{"product_id":"ma-cd40","title":"Anti-human CD40 IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 2G8\/E5) obtained by immunization of mice with human CD40. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in ELISA and flow cytometry studies. It recognizes CD40, a 50 kDa glycoprotein, member of the TNF receptor family, expressed on antigen-presenting cells such as B cells, macrophages, dendritic cells and thymic epithelial cells and overexpressed in a broad range of leukemias, lymphomas and carcinomas. CD40 is activated by gp39 and may stimulate cell growth, differentiation or death.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1.0 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Foy, T.M. et al. (1996) Annu. Rev. Immunol. 14, 591 – 617; Eliopoulos, A.G. \u0026amp; Young, L.S. (2004) Curr. Opin. Pharmacol. 4, 360 – 367; Werneburg, B. et al. (2001) J. Biol. Chem. 276, 43334 – 43342.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD40_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881591598,"sku":"MA-CD40-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd40-200ug.png?v=1788008335","url":"https:\/\/www.australbiologicals.com\/products\/ma-cd40","provider":"Austral Biologicals","version":"1.0","type":"link"}