{"product_id":"ma-cd35","title":"Anti-human Complement Receptor 1 (CR1 or CD35) IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 5H3\/B1) obtained by immunization of mice with a human B cell line. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in ELISA assays. It recognizes human CD35 (CD21), a polymorphic protein expressed as four allelic variants with molecular weight of 160, 190, 220 and 250 kDa. CD35 is expressed on all peripheral blood cells with the exception of platelets, natural killer cells and most T cells. It binds immune complexes opsonized with the activated complement components C3b and C4b, leading to their clearance in the liver and spleen.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1.0 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Krych-Golberg, M. \u0026amp; Atkinson, J.P. (2001) Immunol. Rev. 180, 112 – 122 ; Chen, Z. et al. (2000) Immunol. Rev. 176, 194 – 204.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD35_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881526062,"sku":"MA-CD35-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd35-200ug.png?v=1788008312","url":"https:\/\/www.australbiologicals.com\/products\/ma-cd35","provider":"Austral Biologicals","version":"1.0","type":"link"}