{"product_id":"ma-cd3","title":"Anti-human CD3 IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 3C3\/D4) obtained by immunization of mice with human peripheral T cells. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in flow cytometry studies. It recognizes human CD3. The CD3 antigen is expressed by peripheral T cells, thymocytes, and activated natural killer cells, and is also present in the great majority of T-cell neoplasms. CD3 complex consists of five different polypeptides chains and it is involved in signal transduction to the T cell interior following antigen recognition by the T cell receptor.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 0.5 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Alarcón, B. et al. (2003) Immunol. Rev. 191, 38 – 46 ; Werlen, G. et al. (2003) Science 299, 1859 – 1863 ; Kung, P.C. et al. (1979) Science 206, 347 - 349.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD3_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881493294,"sku":"MA-CD3-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd3-200ug.png?v=1788008334","url":"https:\/\/www.australbiologicals.com\/products\/ma-cd3","provider":"Austral Biologicals","version":"1.0","type":"link"}