{"product_id":"ma-cd11a","title":"Anti-human Lymphocyte Function Associated antigen (LFA-1) alpha Chain; CD11A; Integrin alpha L IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 1F1\/A2) obtained by immunization of mice with human T lymphocytes. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in immunoprecipitation, and flow cytometry. It also inhibits the cytolytic T lymphocyte (CTL) activity. It recognizes CD11a (also known as integrin aL, or LFA-1 a chain), a type I membrane protein (180 kDa) expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. CD11a binds intracellular adhesion molecules (ICAMs), mediates cell adhesion and cytoskeletal organization and plays a role in most immune\/inflammatory responses.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 0.5 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Pribila, J.T. et al. (2004) Ann. Rev. Immunol. 22, 157\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD11A_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881362222,"sku":"MA-CD11A-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd11a-200ug.png?v=1788008312","url":"https:\/\/www.australbiologicals.com\/products\/ma-cd11a","provider":"Austral Biologicals","version":"1.0","type":"link"}