Anti-human Melanoma-Associated Antigen 3 (MAGE-3). IgG fraction (monoclonal)
100 µg
$425.00
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Anti-human Melanoma-Associated Antigen 3 (MAGE-3). IgG fraction (monoclonal)
Catalog no.
MA-741-5
$425.00
IgG fraction from mouse monoclonal antibody (clone 2C7/B7) obtained by immunization of mice with MAGE-3 protein (49 kDa). The IgG fraction was purified using Protein G-Sepharose.
- Storage: Store at -20°C.
- Stability: Stable for at least one year. Avoid repeated freezing and thawing.
- Biological activity: This antibody can be used for ELISA assay (1:4,000 dilution). It recognizes the MAGE-3 protein, a specific antigen that is recognized by autologous cytotoxic T lymphocytes. This cytoplasmatic protein is expressed in melanoma and many malignant tumors, but not in normal tissues except for testes. It may play a role in embryonal development and tumor transformation or aspects of tumor progression.
- Formulation: Solution at 1.0 mg/mL in PBS.
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References: Chomez, P. et al. (2001) Cancer Res. 61, 5544 - 5551.
Gaugler, B. et al. (1994) J. Exp. Med. 179, 921 - 930.