Anti-human Melanoma-Associated Antigen 1 (MAGE-1). IgG fraction (monoclonal)

IgG fraction from mouse monoclonal antibody (clone 3H9/F9) obtained by immunization of mice with MAGE-1 protein (48 kDa). The IgG fraction was purified using Protein G-Sepharose.

• Storage: Store at -20°C.
• Stability: Stable for at least one year. Avoid repeated freezing and thawing.
• Biological activity: This antibody can be used for ELISA assay (1:4,000 dilution) and Western Blot (1:2,000 dilution). It recognizes the MAGE-1 protein, a specific antigen that is recognized by autologous cytotoxic T lymphocytes. This cytoplasmatic protein is expressed in melanoma and many malignant tumors, but not in normal tissues except for testes. It may play a role in embryonal development and tumor transformation or aspects of tumor progression.
• Formulation: Solution at 0.5 mg/mL in PBS
• References: Chomez, P. et al. (2001) Cancer Res. 61, 5544 - 5551.
  De Smet, C. et.al (1996) Proc. Natl. Acad. Sci. USA 93, 7149 - 53.
  Ding, M. et al (1994) Biochem. Biophys. Res. Commun. 202, 549-
  555.

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