Anti-human Vascular Cell Adhesion Protein 1(VCAM-1 or CD106). IgG fraction (monoclonal)
200 µg
$275.00
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Anti-human Vascular Cell Adhesion Protein 1(VCAM-1 or CD106). IgG fraction (monoclonal)
Catalog no.
MA-4011-6
$275.00
IgG fraction from mouse monoclonal antibody (clone 6G10/8) obtained by immunization of mice with human umbilical vein endothelial cells (HUVEC) activated with a TNF. The IgG fraction was purified using Protein G-Sepharose.
- Biological activity: This antibody can be used for functional studies of cell adhesion molecules. VCAM-1 is the receptor for ß-1 integrin VL4 on leukocytes and mediates both adhesion and signal transduction. The VCAM1-VL4 interaction may play a patho-physiologic role both in immune responses and in leukocyte emigration to sites of inflammation. This interaction is important in the specific tumor destruction.
- Formulation: Solution at 1.0 mg/mL in PBS
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References: Jin, Z. et al. (2004) Int. J. Cancer 111, 558 - 567.
Hession, C. et al. (1991) J. Biol. Chem. 266, 6682 - 6685.