{"product_id":"ma-051","title":"Anti-Human IGF-I, IgG Fraction, Monoclonal","description":"\u003cp\u003eAnti-human IGF-I IgG fraction is a monoclonal antibody raised against purified human recombinant IGF-I expressed in yeast cells. The antigen was purified by sequential chromatography. The monoclonal antibody is purified using Protein G.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e At least 1 year at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e Using a 1:100 dilution, together with the alkaline phosphatase detection system, this antibody reacts positively by Western blot to both IGF-I and IGF-II. This monoclonal antibody also recognizes recombinant IGF-I by ELISA.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e IgG fraction. Frozen liquid. 0.25 mg\/mL. Formulated in 0.1M Tris-HCl (pH 7.5)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c!-- AB_PUBLISHED_USE_START --\u003e\n\u003csection class=\"ab-published-use ab-published-use-complete\"\u003e\n\u003ch3 id=\"ab-published-use-ma-051\"\u003ePublications using Austral Biologicals MA-051\u003c\/h3\u003e\n\u003cp\u003eThe following scientific publications report use the anti-human IGF-I monoclonal antibody from Austral Biologicals:\u003c\/p\u003e\n\u003col class=\"ab-publication-list ab-publication-list-complete\"\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/doi.org\/10.1083\/jcb.144.5.1069\" rel=\"noopener\" target=\"_blank\"\u003eType IIA procollagen containing the cysteine-rich amino propeptide is deposited in the extracellular matrix of prechondrogenic tissue and binds to TGF-beta1 and BMP-2\u003c\/a\u003e. \u003cspan class=\"ab-publication-citation\"\u003eZhu et al., Journal of Cell Biology 144(5):1069-1080 (1999).\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/doi.org\/10.1152\/ajprenal.1997.273.6.F899\" rel=\"noopener\" target=\"_blank\"\u003eHeparin binding domain of insulin-like growth factor binding protein-5 stimulates mesangial cell migration\u003c\/a\u003e. \u003cspan class=\"ab-publication-citation\"\u003eAbrass et al., American Journal of Physiology-Renal Physiology 273(6):F899-F906 (1997).\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/section\u003e\n\u003c!-- AB_PUBLISHED_USE_END --\u003e\n\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-051_Datasheet.pdf\" rel=\"noopener\" target=\"_blank\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"100 µg","offer_id":52518880117038,"sku":"MA-051-5","price":425.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-051-100ug.png?v=1788008359","url":"https:\/\/www.australbiologicals.com\/products\/ma-051","provider":"Austral Biologicals","version":"1.0","type":"link"}