{"product_id":"herm-1831","title":"Anti-Human Endogenous Retrovirus Type K (HERV K) Capsid Protein, IgG Fraction,  Monoclonal, Clone 3E11\/I8","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 3E11\/I8) obtained by immunization of mice with HERV K capsid antigen (74 kDa). The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in ELISA assays (1:8,000 dilution) and Western Blot analysis (1:10,000 dilution).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1.0 mg\/mL in PBS.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003cbr\u003e\u003cbr\u003e\u003c\/strong\u003e1. Toenjes, R.R. et al. (1997) Virology 233, 280 - 291.\u003cbr\u003e2. Barbulescu, M. et al. (1999) Curr. Biol. 9, 861 - 868.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c!-- AB_PUBLISHED_USE_START --\u003e\n\u003csection class=\"ab-published-use ab-published-use-complete\"\u003e\n\u003ch3 id=\"ab-published-use-herm-1831\"\u003ePublications using Austral Biologicals HERM-1831-5\u003c\/h3\u003e\n\u003cp\u003eThe following scientific publications report experimental use of HERM-1831-5:\u003c\/p\u003e\n\u003col class=\"ab-publication-list ab-publication-list-complete\"\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/doi.org\/10.1111\/acel.70352\" rel=\"noopener\" target=\"_blank\"\u003eA Novel Human Cellular System for Studying Normal Aging and for Anti-Aging Discovery\u003c\/a\u003e. \u003cspan class=\"ab-publication-citation\"\u003eFeng et al., Aging Cell 25(2):e70352 (2026).\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/doi.org\/10.3389\/fmicb.2025.1604022\" rel=\"noopener\" target=\"_blank\"\u003eActivation of human endogenous retroviruses by Sox proteins induces cell apoptosis via the caspase-3 pathway\u003c\/a\u003e. \u003cspan class=\"ab-publication-citation\"\u003eHossain et al., Frontiers in Microbiology 16:1604022 (2025).\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/doi.org\/10.1016\/j.cell.2023.01.011\" rel=\"noopener\" target=\"_blank\"\u003eBat pluripotent stem cells reveal unusual entanglement between host and viruses\u003c\/a\u003e. \u003cspan class=\"ab-publication-citation\"\u003eDéjosez et al., Cell 186(5):957-974.e28 (2023).\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/doi.org\/10.7759\/cureus.26525\" rel=\"noopener\" target=\"_blank\"\u003eDolutegravir Inhibits Proliferation and Motility of BT-20 Tumor Cells Through Inhibition of Human Endogenous Retrovirus Type K\u003c\/a\u003e. \u003cspan class=\"ab-publication-citation\"\u003eLi et al., Cureus 14(7):e26525 (2022).\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/doi.org\/10.1186\/s12977-017-0351-8\" rel=\"noopener\" target=\"_blank\"\u003eMolecular mechanisms by which HERV-K Gag interferes with HIV-1 Gag assembly and particle infectivity\u003c\/a\u003e. \u003cspan class=\"ab-publication-citation\"\u003eMonde et al., Retrovirology 14(1):27 (2017).\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/doi.org\/10.1128\/jvi.07215-11\" rel=\"noopener\" target=\"_blank\"\u003eExpression of human endogenous retrovirus type K (HML-2) is activated by the Tat protein of HIV-1\u003c\/a\u003e. \u003cspan class=\"ab-publication-citation\"\u003eGonzalez-Hernandez et al., Journal of Virology 86(15):7790-7805 (2012).\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/doi.org\/10.1128\/JVI.00301-12\" rel=\"noopener\" target=\"_blank\"\u003eHuman endogenous retrovirus K Gag coassembles with HIV-1 Gag and reduces the release efficiency and infectivity of HIV-1\u003c\/a\u003e. \u003cspan class=\"ab-publication-citation\"\u003eMonde et al., Journal of Virology 86(20):11194-11208 (2012).\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/doi.org\/10.1186\/1750-1326-6-44\" rel=\"noopener\" target=\"_blank\"\u003eBovine spongiform encephalopathy infection alters endogenous retrovirus expression in distinct brain regions of cynomolgus macaques (Macaca fascicularis)\u003c\/a\u003e. \u003cspan class=\"ab-publication-citation\"\u003eGreenwood et al., Molecular Neurodegeneration 6(1):44 (2011).\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/section\u003e\n\u003c!-- AB_PUBLISHED_USE_END --\u003e\n\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_HERM-1831_Datasheet.pdf\" rel=\"noopener\" target=\"_blank\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"100 µg","offer_id":52518876184878,"sku":"HERM-1831-5","price":425.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-herm-1831-100ug.png?v=1788008495","url":"https:\/\/www.australbiologicals.com\/products\/herm-1831","provider":"Austral Biologicals","version":"1.0","type":"link"}