Anti-Hepatitis C Virus NS5 Antigen, IgG Fraction, Monoclonal

Publications using Austral Biologicals HCM-131-5

The following scientific publications report use of Austral Biologicals HCM-131-5:

1. Proximity labeling of host factor ANXA3 in HCV infection reveals a novel LARP1 function in viral entry. Bley et al., J Biol Chem 300(5):107286 (2024).
2. Hepatitis C virus infection restricts human LINE-1 retrotransposition in hepatoma cells. Schöbel et al., PLoS Pathog 17(4):e1009496 (2021).
3. Dehydrojuncusol, a Natural Phenanthrene Compound Extracted from Juncus maritimus, Is a New Inhibitor of Hepatitis C Virus RNA Replication. Sahuc et al., J Virol 93(10):e02009-18 (2019).
4. Roles of the 5' Untranslated Region of Nonprimate Hepacivirus in Translation Initiation and Viral Replication. Tanaka et al., J Virol 92(7):e01997-17 (2018).
5. Hepatitis C Virus Subverts Human Choline Kinase-α To Bridge Phosphatidylinositol-4-Kinase IIIα (PI4KIIIα) and NS5A and Upregulates PI4KIIIα Activation, Thereby Promoting the Translocation of the Ternary Complex to the Endoplasmic Reticulum for Viral Replication. Wong MT and Chen SS, J Virol 91(16):e00355-17 (2017).
6. Characterization of miR-122-independent propagation of HCV. Ono et al., PLoS Pathog 13(5):e1006374 (2017).
7. RNA helicase DDX3 maintains lipid homeostasis through upregulation of the microsomal triglyceride transfer protein by interacting with HNF4 and SHP. Tsai et al., Sci Rep 7:41452 (2017).
8. Small heterodimer partner 1 directly interacts with NS5A viral protein and has a key role in HCV related liver cell transformation. Conti et al., Oncotarget 7(51):84575-84586 (2016).
9. Hepatitis C Virus Is Released via a Noncanonical Secretory Route. Bayer et al., J Virol 90(23):10558-10573 (2016).
10. Human Choline Kinase-α Promotes Hepatitis C Virus RNA Replication through Modulation of Membranous Viral Replication Complex Formation. Wong MT and Chen SS, J Virol 90(20):9075-9095 (2016).
11. Identification of a New Benzimidazole Derivative as an Antiviral against Hepatitis C Virus. Vausselin et al., J Virol 90(19):8422-8434 (2016).
12. Septin 9 induces lipid droplets growth by a phosphatidylinositol-5-phosphate and microtubule-dependent mechanism hijacked by HCV. Akil et al., Nat Commun 7:12203 (2016).
13. HCV-Mediated Apoptosis of Hepatocytes in Culture and Viral Pathogenesis. Silberstein et al., PLoS One 11(6):e0155708 (2016).
14. Hepatitis C Virus Activates a Neuregulin-Driven Circuit to Modify Surface Expression of Growth Factor Receptors of the ErbB Family. Stindt et al., PLoS One 11(2):e0148711 (2016).
15. Claudin-6 and Occludin Natural Variants Found in a Patient Highly Exposed but Not Infected with Hepatitis C Virus (HCV) Do Not Confer HCV Resistance In Vitro. Fénéant et al., PLoS One 10(11):e0142539 (2015).
16. Y-Box Binding Protein 1 Stabilizes Hepatitis C Virus NS5A via Phosphorylation-Mediated Interaction with NS5A To Regulate Viral Propagation. Wang et al., J Virol 89(22):11584-11602 (2015).
17. New Insights into the Understanding of Hepatitis C Virus Entry and Cell-to-Cell Transmission by Using the Ionophore Monensin A. Fénéant et al., J Virol 89(16):8346-8364 (2015).
18. NS5A inhibitors impair NS5A-phosphatidylinositol 4-kinase IIIα complex formation and cause a decrease of phosphatidylinositol 4-phosphate and cholesterol levels in hepatitis C virus-associated membranes. Reghellin et al., Antimicrob Agents Chemother 58(12):7128-7140 (2014).
19. Visualization and analysis of hepatitis C virus structural proteins at lipid droplets by super-resolution microscopy. Eggert et al., PLoS One 9(7):e102511 (2014).
20. Nonstructural protein 5A is incorporated into hepatitis C virus low-density particle through interaction with core protein and microtubules during intracellular transport. Lai et al., PLoS One 9(6):e99022 (2014).
21. The intraviral protein interaction network of hepatitis C virus. Hagen et al., Mol Cell Proteomics 13(7):1676-1689 (2014).
22. Lymphocytes as liver damage mirror of HCV related adipogenesis deregulation. Minutolo et al., PLoS One 9(3):e92343 (2014).
23. Novel permissive cell lines for complete propagation of hepatitis C virus. Shiokawa et al., J Virol 88(10):5578-5594 (2014).
24. Innate immune response induced by baculovirus attenuates transgene expression in mammalian cells. Ono et al., J Virol 88(4):2157-2167 (2014).
25. SPOC1-mediated antiviral host cell response is antagonized early in human adenovirus type 5 infection. Schreiner et al., PLoS Pathog 9(11):e1003775 (2013).
26. The antimalarial ferroquine is an inhibitor of hepatitis C virus. Vausselin et al., Hepatology 58(1):86-97 (2013).
27. Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein. Vogt et al., PLoS Pathog 9(4):e1003302 (2013).
28. Diacylglycerol acyltransferase-1 localizes hepatitis C virus NS5A protein to lipid droplets and enhances NS5A interaction with the viral capsid core. Camus et al., J Biol Chem 288(14):9915-9923 (2013).
29. EWI-2wint promotes CD81 clustering that abrogates Hepatitis C Virus entry. Potel et al., Cell Microbiol 15(7):1234-1252 (2013).
30. Expression of microRNA miR-122 facilitates an efficient replication in nonhepatic cells upon infection with hepatitis C virus. Fukuhara et al., J Virol 86(15):7918-7933 (2012).
31. Annexin A2 is involved in the formation of hepatitis C virus replication complex on the lipid raft. Saxena et al., J Virol 86(8):4139-4150 (2012).
32. Proline-serine-threonine phosphatase-interacting protein 2 (PSTPIP2), a host membrane-deforming protein, is critical for membranous web formation in hepatitis C virus replication. Chao et al., J Virol 86(3):1739-1749 (2012).
33. Establishment of a novel permissive cell line for the propagation of hepatitis C virus by expression of microRNA miR122. Kambara et al., J Virol 86(3):1382-1393 (2012).
34. Dysfunction of autophagy participates in vacuole formation and cell death in cells replicating hepatitis C virus. Taguwa et al., J Virol 85(24):13185-13194 (2011).
35. Generation of a cell culture-adapted hepatitis C virus with longer half life at physiological temperature. Kim et al., PLoS One 6(8):e22808 (2011).
36. Interacting regions of CD81 and two of its partners, EWI-2 and EWI-2wint, and their effect on hepatitis C virus infection. Montpellier et al., J Biol Chem 286(16):13954-13965 (2011).
37. Elimination of hepatitis C virus from hepatocytes by a selective activation of therapeutic molecules. Wen et al., PLoS One 6(1):e15967 (2011).
38. Chaperonin TRiC/CCT participates in replication of hepatitis C virus genome via interaction with the viral NS5B protein. Inoue et al., Virology 410(1):38-47 (2011).
39. Heat shock protein 72 is associated with the hepatitis C virus replicase complex and enhances viral RNA replication. Chen et al., J Biol Chem 285(36):28183-28190 (2010).
40. Polo-like kinase 1 is involved in hepatitis C virus replication by hyperphosphorylating NS5A. Chen et al., J Virol 84(16):7983-7993 (2010).
41. Persistent growth of a human plasma-derived hepatitis C virus genotype 1b isolate in cell culture. Silberstein et al., PLoS Pathog 6(5):e1000910 (2010).
42. Identification of GBF1 as a cellular factor required for hepatitis C virus RNA replication. Goueslain et al., J Virol 84(2):773-787 (2010).
43. Knockdown of autophagy-related gene decreases the production of infectious hepatitis C virus particles. Tanida et al., Autophagy 5(7):937-945 (2009).
44. Cochaperone activity of human butyrate-induced transcript 1 facilitates hepatitis C virus replication through an Hsp90-dependent pathway. Taguwa et al., J Virol 83(20):10427-10436 (2009).
45. Naturally occurring hepatitis C virus subgenomic deletion mutants replicate efficiently in Huh-7 cells and are trans-packaged in vitro to generate infectious defective particles. Pacini et al., J Virol 83(18):9079-9093 (2009).
46. Human VAP-C negatively regulates hepatitis C virus propagation. Kukihara et al., J Virol 83(16):7959-7969 (2009).
47. Association of hepatitis C virus replication complexes with microtubules and actin filaments is dependent on the interaction of NS3 and NS5A. Lai et al., J Virol 82(17):8838-8848 (2008).
48. Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly. Appel et al., PLoS Pathog 4(3):e1000035 (2008).
49. A single-amino-acid mutation in hepatitis C virus NS5A disrupting FKBP8 interaction impairs viral replication. Okamoto et al., J Virol 82(7):3480-3489 (2008).
50. Human butyrate-induced transcript 1 interacts with hepatitis C virus NS5A and regulates viral replication. Taguwa et al., J Virol 82(6):2631-2641 (2008).
51. Responses of nontransformed human hepatocytes to conditional expression of full-length hepatitis C virus open reading frame. Tang et al., Am J Pathol 171(6):1831-1846 (2007).
52. Hepatitis C virus nonstructural protein 5A modulates the toll-like receptor-MyD88-dependent signaling pathway in macrophage cell lines. Abe et al., J Virol 81(17):8953-8966 (2007).
53. Monitoring the antiviral effect of alpha interferon on individual cells. Kim et al., J Virol 81(16):8814-8820 (2007).
54. Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90. Okamoto et al., EMBO J 25(20):5015-5025 (2006).
55. Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response. Polyak et al., J Virol 75(13):6095-6106 (2001).