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Hepatitis C Virus E2 Antigen, Recombinant
Catalog no.
HCA-090-2
$395.00
Recombinant HCV (subtype 1a) protein made in CHO cells. Covers from Glu 383 to Ala 745 of the HCV-1a polyprotein.
- Molecular weight: 55 kDa
- Purity: Over 90% pure.
- Storage: Store at -80°C.
- Stability: At least 1 year at -80°C.
- Biological activity: It has a MW of 55,000, however it runs anomalously on PAGE.
- Formulation: Solution at 0.20 mg/mL in 10mM sodium phosphate, 0.1M NaCI, (pH 6.2)
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References:
1. The Genetic Organization and Diversity of Hepatitis C virus. Q-L. Choo et al., Proc. Natl. Acad. Sci. USA 88, 2451 (1991).
2. Hepatitis C viruses. Michael Houghton, In Fields Virology, Third Edition (Fields, B.N; Knipe, D.M. and Howley, P.M. Editors), Raven Publishers, page 1035 (1996)
Publications using HCA-090
The following scientific publications report use of this Austral Biologicals product:
- Plant-based production of virus-like particles from hepatitis C virus. López-Castillo et al., Planta 263(4):86 (2026).
- Mass spectrometric characterization of glycosylation of hepatitis C virus E2 envelope glycoprotein reveals extended microheterogeneity of N-glycans. Iacob et al., J Am Soc Mass Spectrom 19(3):428-444 (2008).
- Characterization of an immunodominant antigenic site on GB virus C glycoprotein E2 that is involved in cell binding. McLinden et al., J Virol 80(24):12131-12140 (2006).