{"product_id":"ci-420","title":"Interleukin-2 (IL-2), Human Recombinant","description":"\u003cp\u003eHuman Interleukin-2 (IL-2) is a lymphokine which biological effects include activation and proliferation of T cells, B cells, and other lymphokine activated killer cells. Human IL-2 is composed of 133 amino acids, including 3 cysteine residues, two of which are involved in a disulfide bond essential for biological activity. Human and murine IL-2 are 62% homologous, and human IL-2 has been found to be active on murine cell lines. Human Interleukin-2 (RECOMBINANT) is produced in genetically engineered Escherichia coli cells, and purified by sequential chromatography.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular weight:\u003c\/strong\u003e 15 kDa\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e Over 95% pure by SDS gel electrophoresis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at +2°C to +8°C\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Several months as formulated, at +2°C to +8°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e The biological activity is determined by a lymphocyte proliferation assay and each vial contains 160,000 IU (International units)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Lyophilized in the presence of stabilizer (mannitol), low levels of SDS (preventing aggregation), and Sodium Phosphate. It can be reconstituted in water giving a pH between 7.2-7.8. There are no preservatives in this formulation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003cbr\u003e\u003cbr\u003e\u003c\/strong\u003e1. Gillis, S., Ferm, M.M., Ou, W., and Smith, K.A., The Journal of Immunology, (1978) Vol 120, No. 6, June, 2027-2032\u003cbr\u003e2. Mosmann, T., Journal of Immunological Methods, (1983) Vol 65, 55-63\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_CI-420_Datasheet.pdf\" rel=\"noopener\" target=\"_blank\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"10 µg","offer_id":52518872842542,"sku":"CI-420-3","price":100.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ci-420-10ug.png?v=1788008726","url":"https:\/\/www.australbiologicals.com\/products\/ci-420","provider":"Austral Biologicals","version":"1.0","type":"link"}