{"product_id":"bp-380","title":"IGF-Binding Protein 6, Human Recombinant","description":"\u003cp\u003eHuman IGF-Binding protein 6 is produced in genetically engineered yeast, and purified by affinity chromatography and HPLC.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMolecular weight:\u003c\/strong\u003e 24 kDa\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity:\u003c\/strong\u003e Over 90% pure by SDS gel electrophoresis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at +4°C. Reconstitution is best in water or buffer near neutral pH. After reconstitution, storage in aliquots at -80°C is recommended.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Several months at +4°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e Binding activity of human IGF-BP 6 is determined by the inhibition activity of both IGF I and II.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Lyophilized powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003cbr\u003e\u003cbr\u003e\u003c\/strong\u003e1.Kiefer, M.C., Schmid, C., Waldvogel, M., Sclapfer, I., Futo, E., Maziarz, F.R., Green, K., Barr, P.J. and Zapf, J. (1992) The Journal of Biological Chemistry, Vol 267, No 18, 12692-12699\u003cbr\u003e2. Rechler M.M. and Brown A.L. (1992) Growth Regulation, 2, 55.\u003cbr\u003e3. Modern Concepts of Insulin-Like Growth Factor. Ed. E. Martin Spencer, M.D. (1991). Elsevier Science Publ., pages 311-415\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c!-- AB_PUBLISHED_USE_START --\u003e\n\u003csection class=\"ab-published-use ab-published-use-complete\"\u003e\n\u003ch3 id=\"ab-published-use-bp-380\"\u003ePublications using BP-380\u003c\/h3\u003e\n\u003cp\u003eThe following scientific publication report use of this Austral Biologicals product:\u003c\/p\u003e\n\u003col class=\"ab-publication-list ab-publication-list-complete\"\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/doi.org\/10.1074\/jbc.274.10.6711\" rel=\"noopener\" target=\"_blank\"\u003eInteractions of high affinity insulin-like growth factor-binding proteins with the type V transforming growth factor-beta receptor in mink lung epithelial cells\u003c\/a\u003e. \u003cspan class=\"ab-publication-citation\"\u003eLeal et al., J Biol Chem 274(10):6711-6717 (1999).\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/section\u003e\n\u003c!-- AB_PUBLISHED_USE_END --\u003e\n\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_BP-380_Datasheet.pdf\" rel=\"noopener\" target=\"_blank\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"5 µg","offer_id":52518872809774,"sku":"BP-380-2","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-bp-380-5ug.png?v=1788008726","url":"https:\/\/www.australbiologicals.com\/products\/bp-380","provider":"Austral Biologicals","version":"1.0","type":"link"}