{"title":"Immunology \u0026 Cell-Marker Antibodies","description":null,"products":[{"product_id":"ma-4001","title":"Anti-human Integrin Beta 1 (CD29). IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 2A2\/I6) obtained by immunization of mice with human HeLa cells. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used for ELISA assay. Integrins are a family of divalent-cation dependent cell adhesion receptors that express a conserved ß chain (ß1 or CD29, and ß2 or CD13) associated non-covalently with different a chains. Integrin ß1 mediates the leukocyte adhesion to extra-cellular matrix proteins and endothelium to regulate the efficiency and specificity of trafficking into secondary lymphoid organs and peripheral tissue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 0.5 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Pribila, J.T. et al. (2004) Ann. Rev. Immunol. 22, 157 - 180.\u003cbr\u003eBalzac, F. et al. (1993) J. Cell Biol. 121, 171 - 178.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-4001_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518880739630,"sku":"MA-4001-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-4001-200ug.png?v=1788008323"},{"product_id":"ma-4011","title":"Anti-human Vascular Cell Adhesion Protein 1(VCAM-1 or CD106). IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 6G10\/8) obtained by immunization of mice with human umbilical vein endothelial cells (HUVEC) activated with a TNF. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used for functional studies of cell adhesion molecules. VCAM-1 is the receptor for ß-1 integrin VL4 on leukocytes and mediates both adhesion and signal transduction. The VCAM1-VL4 interaction may play a patho-physiologic role both in immune responses and in leukocyte emigration to sites of inflammation. This interaction is important in the specific tumor destruction.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1.0 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Jin, Z. et al. (2004) Int. J. Cancer 111, 558 - 567.\u003cbr\u003eHession, C. et al. (1991) J. Biol. Chem. 266, 6682 - 6685.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-4011_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518880772398,"sku":"MA-4011-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-4011-200ug.png?v=1788008347"},{"product_id":"ma-4021","title":"Anti-mouse Cathepsin S. IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 4B3\/A8) obtained by immunization of mice with Cathepsin S. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used for ELISA assay. Cathepsin S is a cysteine proteinase that is reported to be involved in antigen presentation and may play a role in tumor progression.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1.0 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Lennon-Duménil, A.M. et al. (2002) J. Exp. Med. 196, 529 - 539.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-4021_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"100 µg","offer_id":52518880805166,"sku":"MA-4021-5","price":425.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-4021-100ug.png?v=1788008354"},{"product_id":"ma-4031","title":"Anti-human Class II Transactivator (Ciita) IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 7D3\/A1) obtained by immunization of mice with recombinant human CIITA fusion protein. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in ELISA, Western Blot, and immunoprecipitation. It recognizes CIITA, a non-DNA binding coactivator considered as the master regulator of basal and induced MHC class II specific gene expression. CIITA ensures a tight transcriptional control of these antigen-presenting genes to meet with local requirements for an adequate immune response.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1.0 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e LeibundGut-Landmann, S. et al. (2004) Eur. J. Immunol. 34, 1513 – 1525; Van den Elsen, P. et al. (2004) Curr. Opin. Immunol. 16, 67 – 75 ; Naves, R. et al. (2002) Int. Immunol. 14, 481 – 491.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-4031_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"100 µg","offer_id":52518880837934,"sku":"MA-4031-5","price":425.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-4031-100ug.png?v=1788008346"},{"product_id":"ma-404","title":"Anti-human b-2-Microglobulin IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 3G8\/B2) obtained by immunization of mice with human EBB-B cell line. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in ELISA and flow cytometry studies. It recognizes b-2-microglobulin, a cell membrane protein (12 kDa) non-covalent associated to MHC class I molecules. b-2-microglobulin associates with the a3 subdomain of the a heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class I molecules\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 0.5 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Paulsson, K.M. (2004) Cell. Mol. Life. Sci. 61, 2446 – 2460; Pamer, E. \u0026amp; Cresswell, P. (1998) Ann. Rev. Immunol. 16, 323 – 358; Solheim, J.C. (1999) Immunol. Rev. 172, 11 – 19.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-404_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"100 µg","offer_id":52518880870702,"sku":"MA-404-5","price":425.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-404-100ug.png?v=1788008346"},{"product_id":"ma-481","title":"Anti-human Interleukin 8 IgG fraction (monoclonal)","description":"\u003cp\u003eAnti-human IL8 IgG (IgG3) fraction is a mouse monoclonal antibody prepared against highly purified recombinant Il-8. The antibody fraction was purified using Protein G.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e At least 1 year at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This monoclonal antibody recognizes Interleukin 8 protein using an ELISA format.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e IgG (IgG-3) fraction. Frozen liquid; 0.25 mg\/mL. Total volume is 400 µL. Formulated in 0.1M Tris-HCl, pH 7.0\u003c\/li\u003e\n  \u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-481_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"100 µg","offer_id":52518880936238,"sku":"MA-481-5","price":425.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-481-100ug.png?v=1788008346"},{"product_id":"ma-cd11a","title":"Anti-human Lymphocyte Function Associated antigen (LFA-1) alpha Chain; CD11A; Integrin alpha L IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 1F1\/A2) obtained by immunization of mice with human T lymphocytes. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in immunoprecipitation, and flow cytometry. It also inhibits the cytolytic T lymphocyte (CTL) activity. It recognizes CD11a (also known as integrin aL, or LFA-1 a chain), a type I membrane protein (180 kDa) expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. CD11a binds intracellular adhesion molecules (ICAMs), mediates cell adhesion and cytoskeletal organization and plays a role in most immune\/inflammatory responses.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 0.5 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Pribila, J.T. et al. (2004) Ann. Rev. Immunol. 22, 157\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD11A_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881362222,"sku":"MA-CD11A-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd11a-200ug.png?v=1788008312"},{"product_id":"ma-cd16","title":"Anti-human CD16 (Fc receptor III) IgG fraction (monoclonal)","description":"  \u003cp\u003eAnti-CD16 antibody IgG fraction is a murine monoclonal antibody raised against human Fc gamma receptor III. This antibody was isolated from bispecific monoclonal antibody 2B1 quadroma cell. It is purified by anion exchange chromatography.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at 2 to 8°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e At least 2 years at 2 to 8°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This monoclonal antibody recognizes the native human Fc gamma RIII, with high affinity, on ELISA.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e IgG fraction in Liquid. 0.27 mg\/mL (740 µL total volume). Formulated in 0.02 M Tris-HCl\/0.12 M NaCl (pH 8.5).\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD16_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881394990,"sku":"MA-CD16-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd16-200ug.png?v=1788008323"},{"product_id":"ma-cd2","title":"Anti-human Lymphocyte Function Associated antigen 2 (LFA-2); CD2; (E-Rosette Receptor) IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 8A2\/H11) obtained by immunization of mice with human T lymphocytes. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in immunoprecipitation, and flow cytometry. It also inhibits the cytolic T lymphocyte (CTL) activity. It recognizes CD2 (also known as LFA-2, or E-rosette receptor), a 50 kDa transmembrane glycoprotein expressed on T cells, NK cells, cortical thymocytes and most malignant cells of T cell origin. It binds CD58 (LFA-3) to mediate cell adhesion and it is also receptor for CD59, and CD48. CD2 plays a critical role in activation of T cells.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 0.5 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e van der Merwe, P. A. \u0026amp; Davis S.J. (2003) Annu. Rev. Immunol. 21, 659 – 684 ; Hahn, W. et al. (1992) Science, 256, 1805 – 1807 ; Moingeon, P. et al. (1989) Immunol. Rev. 111, 111 – 144.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD2_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881427758,"sku":"MA-CD2-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd2-200ug.png?v=1788008313"},{"product_id":"ma-cd21","title":"Anti-human Complement Receptor 2 (CR2 or CD21) IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 8B5\/H5) obtained by immunization of mice with a human B cell line. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in ELISA assays. It recognizes human CD21 (CR2), a 145 kDa type I integral membrane glycoprotein. CD21 is a receptor for the C3d complement fragment and for the Epstein-Barr virus, expressed on mature B cells, follicular dendritic cells, and some epithelial cells. It plays a role in B cell activation and proliferation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1.0 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Carroll, M.C. (2004) Mol. Immunol. 41, 141 – 146; Hannan, J. et al. (2002) Biochem. Soc. Trans. 30, 983 – 989; Weis, J.J. et al. (1984) Proc. Natl. Acad. Sci. USA, 81, 881 – 885.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD21_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881460526,"sku":"MA-CD21-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd21-200ug.png?v=1788008314"},{"product_id":"ma-cd3","title":"Anti-human CD3 IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 3C3\/D4) obtained by immunization of mice with human peripheral T cells. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in flow cytometry studies. It recognizes human CD3. The CD3 antigen is expressed by peripheral T cells, thymocytes, and activated natural killer cells, and is also present in the great majority of T-cell neoplasms. CD3 complex consists of five different polypeptides chains and it is involved in signal transduction to the T cell interior following antigen recognition by the T cell receptor.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 0.5 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Alarcón, B. et al. (2003) Immunol. Rev. 191, 38 – 46 ; Werlen, G. et al. (2003) Science 299, 1859 – 1863 ; Kung, P.C. et al. (1979) Science 206, 347 - 349.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD3_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881493294,"sku":"MA-CD3-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd3-200ug.png?v=1788008334"},{"product_id":"ma-cd35","title":"Anti-human Complement Receptor 1 (CR1 or CD35) IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 5H3\/B1) obtained by immunization of mice with a human B cell line. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in ELISA assays. It recognizes human CD35 (CD21), a polymorphic protein expressed as four allelic variants with molecular weight of 160, 190, 220 and 250 kDa. CD35 is expressed on all peripheral blood cells with the exception of platelets, natural killer cells and most T cells. It binds immune complexes opsonized with the activated complement components C3b and C4b, leading to their clearance in the liver and spleen.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1.0 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Krych-Golberg, M. \u0026amp; Atkinson, J.P. (2001) Immunol. Rev. 180, 112 – 122 ; Chen, Z. et al. (2000) Immunol. Rev. 176, 194 – 204.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD35_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881526062,"sku":"MA-CD35-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd35-200ug.png?v=1788008312"},{"product_id":"ma-cd4","title":"Anti-human CD4 (soluble receptor) IgG fraction (monoclonal)","description":"\u003cp\u003eAnti-CD4 antibody IgG fraction is a murine monoclonal antibody raised against a soluble human recombinant CD-4 expressed in CHO cells. It is purified from ascites fluids by affinity chromatography on protein G Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e At least 1 year at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This monoclonal antibody recognizes the native and recombinant CD-4 (58 kD), with high affinity, on ELISA. This monoclonal antibody does not neutralize the binding of recombinant HIV gp120 to CD-4.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e IgG-1 fraction in liquid. 1.0 mg\/mL (200 µL total volume). Formulated in 0.1 M Tris-HCl (pH 7.5).\u003c\/li\u003e\n  \u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD4_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881558830,"sku":"MA-CD4-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd4-200ug.png?v=1788008312"},{"product_id":"ma-cd40","title":"Anti-human CD40 IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 2G8\/E5) obtained by immunization of mice with human CD40. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in ELISA and flow cytometry studies. It recognizes CD40, a 50 kDa glycoprotein, member of the TNF receptor family, expressed on antigen-presenting cells such as B cells, macrophages, dendritic cells and thymic epithelial cells and overexpressed in a broad range of leukemias, lymphomas and carcinomas. CD40 is activated by gp39 and may stimulate cell growth, differentiation or death.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1.0 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Foy, T.M. et al. (1996) Annu. Rev. Immunol. 14, 591 – 617; Eliopoulos, A.G. \u0026amp; Young, L.S. (2004) Curr. Opin. Pharmacol. 4, 360 – 367; Werneburg, B. et al. (2001) J. Biol. Chem. 276, 43334 – 43342.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD40_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881591598,"sku":"MA-CD40-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd40-200ug.png?v=1788008335"},{"product_id":"ma-cd45","title":"Anti-human CD45 (Leukocyte Common Antigen) IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 8G3\/A1) obtained by immunization of mice with human lymphocytes. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in flow cytometry studies. It recognizes all isoforms of the CD45 (LCA). CD45 is a transmembrane tyrosine phosphatase, expressed on nucleated hematopoitic cells, which can exist in at least nine different isoforms resulting from tissue-specific alternative RNA splicing. CD45 functions as a leukocyte membrane receptor signal transduction. It plays an essential role in the regulation of leukocyte activation, development, and function.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1.0 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Mustelin, T. et al. (2004) Mol. Immunol. 41, 687 – 700 ; Trowbridge, I.S. et al. (1994) Annu. Rev. Immunol. 12, 85 – 116 ; Justement, L.B. et al. (1991) Science 252, 1839 – 1842.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD45_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881624366,"sku":"MA-CD45-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd45-200ug.png?v=1788008295"},{"product_id":"ma-cd58","title":"Anti-human Lymphocyte Function Associated Antigen 3 (LFA-3); CD58 IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 2B2\/D3) obtained by immunization of mice with human T lymphocytes. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in immunoprecipitation, and flow cytometry, it also inhibits the cytolytic T lymphocyte (CTL) activity. It recognizes CD58 (also known as LFA-3), a 60-70 kDa membrane glycoprotein member of the immunoglobulin super family. CD58 is expressed on haemopoetic cells and it functions as an adhesion molecule mediating a co-stimulatory signal through CD2.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 1.0 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e van der Merwe, P.A. \u0026amp; Davis, S.J. (2003) Annu. Rev. Immunol. 21, 659 – 684; Wang, J-H. et al. (1999) Cell 97, 791 – 803; Wallner, B.P. et al. (1987) J. Exp. Med. 166, 923 – 932.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD58_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881657134,"sku":"MA-CD58-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd58-200ug.png?v=1788008295"},{"product_id":"ma-cd8","title":"Anti-human T-Cell Surface Glycoprotein CD8. IgG fraction (Monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 1C8\/D8) obtained by immunization of mice with human CD8+ T- lymphocyte. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used for ELISA assay. Human CD8 is expressed either as an aß heterodimer or an aa homodimer by the cytotoxic\/suppressor subset of T-cells and weakly by NK cells. CD8 acts as co-receptor in class I MHC-restricted antigen-induced T cell activation (binds to class I MHC molecules). It also participates in the thymocyte development.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 0.5 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Ellmeier, W. el. al. (1999) Annu, Rev. Immunol. 17, 523 - 554.\u003cbr\u003eLittman, D.R. et al. (1985) Cell 40, 237 - 246.\u003cbr\u003ePerussia, B. et al. (1983) J. Immunol. 131, 223 - 231.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-CD8_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"200 µg","offer_id":52518881689902,"sku":"MA-CD8-6","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-cd8-200ug.png?v=1788008296"},{"product_id":"ma-mhc1","title":"Anti-human MHC Class I IgG fraction (monoclonal)","description":"\u003cp\u003eIgG fraction from mouse monoclonal antibody (clone 1A6\/C2) obtained by immunization of mice with human tonsil leukocyte membrane preparation. The IgG fraction was purified using Protein G-Sepharose.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at -20°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStability:\u003c\/strong\u003e Stable for at least one year. Avoid repeated freezing and thawing\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiological activity:\u003c\/strong\u003e This antibody can be used in ELISA, flow cytometry, immunohistochemistry (frozen sections) and Western blot analysis. It recognizes Major Histocompatibility Complex class I (MHC, human leukocyte antigen) MHC class I is a dimmer composed of two polypeptide chains, an a chain (44 kDa) and a non-covalently associated protein, b2 microglobulin (12 kDa). The antibody reacts with a monomorphic epitope on the a chain polypeptide of human class I HLA molecules (HLA-A,B,C).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFormulation:\u003c\/strong\u003e Solution at 0.5 mg\/mL in PBS\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReferences:\u003c\/strong\u003e Paulsson, K.M. (2004) Cell. Mol. Life. Sci. 61, 2446 –2460; Shields, M.J. \u0026amp; Ribaudo, R.K. (1998) Tissue Antigens 51, 567-570; Bjorkman, P.J. et al. (1987) Nature 329, 506 – 512.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp class=\"ab-datasheet-link\"\u003e\u003ca href=\"https:\/\/helix-chartreuse-ypja.squarespace.com\/s\/Austral_Biologicals_MA-MHC1_Datasheet.pdf\" target=\"_blank\" rel=\"noopener\"\u003e\u003cstrong\u003eDownload technical datasheet (PDF)\u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Austral Biologicals","offers":[{"title":"100 µg","offer_id":52518881722670,"sku":"MA-MHC1-5","price":425.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/2846\/3918\/files\/austral-biologicals-ma-mhc1-100ug.png?v=1788008295"}],"url":"https:\/\/www.australbiologicals.com\/collections\/immunology-cell-marker-antibodies.oembed","provider":"Austral Biologicals","version":"1.0","type":"link"}