AUSTRAL Biologicals Catalog

Product Sheet: Interleukin-2 human (IL-2) (RECOMBINANT)

Catalog NumberCI-420-3
Product IdCI-420-3
Product NameInterleukin-2 human (IL-2) (RECOMBINANT)
Temperature+2°C to +8°C
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryGrowth Factors/Cytokines/Enzymes
DescriptionHuman Interleukin-2 (IL-2) is a lymphokine which biological effects include activation and proliferation of T cells, B cells, and other lymphokine activated killer cells. Human IL-2 is composed of 133 amino acids, including 3 cysteine residues, two of which are involved in a disulfide bond essential for biological activity. Human and murine IL-2 are 62% homologous, and human IL-2 has been found to be active on murine cell lines. Human Interleukin-2 (RECOMBINANT) is produced in genetically engineered Escherichia coli cells, and purified by sequential chromatography.
Mol Weight15 KDa
PurityOver 95% pure by SDS gel electrophoresis.
StorageStore at +2°C to +8°C
StabilitySeveral months as formulated, at +2°C to +8°C.
Biological ActivityThe biological activity is determined by a lymphocyte proliferation assay and each vial contains 160,000 IU (International units)
FormulationLyophilized in the presence of stabilizer (mannitol), low levels of SDS (preventing aggregation), and Sodium Phosphate. It can be reconstituted in water giving a pH between 7.2-7.8. There are no preservatives in this formulation.
References1. Gillis, S., Ferm, M.M., Ou, W., and Smith, K.A., The Journal of Immunology, (1978) Vol 120, No. 6, June, 2027-2032
2. Mosmann, T., Journal of Immunological Methods, (1983) Vol 65, 55-63
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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