AUSTRAL Biologicals Catalog

Product Sheet: Human transforming growth factor beta-2 (TGF - beta-2) recombinant

Catalog Number	GF-240-2
Product Id	GF-240-2
Product Name	Human transforming growth factor beta-2 (TGF - beta-2) recombinant
Temperature	-80°C
Unit	5µg
Price	250
Availability	Available
Category	Growth Factors, Cytokines, Receptors and their Antibodies
Subcategory	Growth Factors/Cytokines/Enzymes
Description	Human Transforming Growth Factor beta2 (TGF- beta2) is stimulatory for cells of mesenchymal origin and inhibitory for cells of epithelial or neuroectodermal origin. Mature TGF- beta2 is a disulfide-linked homodimer of two chains composed of 112 amino acid residues each. There is a 70% homology between human TGF- beta2 and human TGF- beta1. Human TGF- beta2 is produced in genetically engineered e. coli bacteria, and purified by sequential chromatography.
Isotype	N/A
Mol Weight	25 KDa (dimeric protein)
Purity	Over 98% pure by non-reduced SDS gel electrophoresis.
Storage	Store at -80°C.
Stability	Several months at -80°C.
Biological Activity	The biological activity of human TGF-&# beta2 is determined by measuring the acidification of the culture medium (Rat-1 cells) exposed to the growth factor.
Formulation	1 mg/ml (pH 2.5). CAUTION: Since the volume supplied is small, we advise our customers to dilute this material to a working stock solution. To remove partial aliquots in not recommended.
References	1. Moustakas, A., Lin, H.Y., Henis, Y.I., Plamondon, J., O'Conner-McCourt, M.D., and Lodish, H.F., (1993) The Journal of Biological Chemistry, Vol 268, 30, October, 22215-22218. 2. Geiser, A.G., Burmester, J.K., Webbink, R., Roberts, A.B., and Sporn, M.B., (1992). The Journal of Biological Chemistry, Vol 267, 4, February, 2588-2593.

All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.