AUSTRAL Biologicals Catalog

Product Sheet: Human transforming growth factor beta-2 (TGF - beta-2) recombinant

Catalog NumberGF-240-2
Product IdGF-240-2
Product NameHuman transforming growth factor beta-2 (TGF - beta-2) recombinant
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryGrowth Factors/Cytokines/Enzymes
DescriptionHuman Transforming Growth Factor beta2 (TGF- beta2) is stimulatory for cells of mesenchymal origin and inhibitory for cells of epithelial or neuroectodermal origin. Mature TGF- beta2 is a disulfide-linked homodimer of two chains composed of 112 amino acid residues each. There is a 70% homology between human TGF- beta2 and human TGF- beta1. Human TGF- beta2 is produced in genetically engineered e. coli bacteria, and purified by sequential chromatography.
Mol Weight25 KDa (dimeric protein)
PurityOver 98% pure by non-reduced SDS gel electrophoresis.
StorageStore at -80°C.
StabilitySeveral months at -80°C.
Biological ActivityThe biological activity of human TGF-&# beta2 is determined by measuring the acidification of the culture medium (Rat-1 cells) exposed to the growth factor.
Formulation1 mg/ml (pH 2.5). CAUTION: Since the volume supplied is small, we advise our customers to dilute this material to a working stock solution. To remove partial aliquots in not recommended.
References1. Moustakas, A., Lin, H.Y., Henis, Y.I., Plamondon, J., O'Conner-McCourt, M.D., and Lodish, H.F., (1993) The Journal of Biological Chemistry, Vol 268, 30, October, 22215-22218.
2. Geiser, A.G., Burmester, J.K., Webbink, R., Roberts, A.B., and Sporn, M.B., (1992). The Journal of Biological Chemistry, Vol 267, 4, February, 2588-2593.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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