AUSTRAL Biologicals Catalog

Product Sheet: Anti-human Vascular Cell Adhesion Protein 1(VCAM-1 or CD106). IgG fraction (monoclonal)

Catalog NumberMA-4011-6
Product IdMA-4011-6
Product NameAnti-human Vascular Cell Adhesion Protein 1(VCAM-1 or CD106). IgG fraction (monoclonal)
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryMonoclonal Antibodies (Immunology Antigens)
DescriptionIgG fraction from mouse monoclonal antibody (clone 6G10/8) obtained by immunization of mice with human umbilical vein endothelial cells (HUVEC) activated with a TNF. The IgG fraction was purified using Protein G-Sepharose.
Biological ActivityThis antibody can be used for functional studies of cell adhesion molecules. VCAM-1 is the receptor for ß-1 integrin VL4 on leukocytes and mediates both adhesion and signal transduction. The VCAM1-VL4 interaction may play a patho-physiologic role both in immune responses and in leukocyte emigration to sites of inflammation. This interaction is important in the specific tumor destruction.
FormulationSolution at 1.0 mg/mL in PBS
ReferencesJin, Z. et. al. (2004) Int. J. Cancer 111, 558 - 567.
Hession, C. et. al. (1991) J. Biol. Chem. 266, 6682 - 6685.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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