AUSTRAL Biologicals Catalog

Product Sheet: Anti-human Melanoma-Associated Antigen 3 (MAGE-3). IgG fraction (monoclonal)

Catalog NumberMA-741-5
Product IdMA-741-5
Product NameAnti-human Melanoma-Associated Antigen 3 (MAGE-3). IgG fraction (monoclonal)
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryMonoclonal Antibodies (Cancer Antigens)
DescriptionIgG fraction from mouse monoclonal antibody (clone 2C7/B7) obtained by immunization of mice with MAGE-3 protein (49 kDa). The IgG fraction was purified using Protein G-Sepharose.
StorageStore at -20°C.
StabilityStable for at least one year. Avoid repeated freezing and thawing.
Biological ActivityThis antibody can be used for ELISA assay (1:4,000 dilution). It recognizes the MAGE-3 protein, a specific antigen that is recognized by autologous cytotoxic T lymphocytes. This cytoplasmatic protein is expressed in melanoma and many malignant tumors, but not in normal tissues except for testes. It may play a role in embryonal development and tumor transformation or aspects of tumor progression.
FormulationSolution at 1.0 mg/mL in PBS.
ReferencesChomez, P. et. al. (2001) Cancer Res. 61, 5544 - 5551.
Gaugler, B. et. al. (1994) J. Exp. Med. 179, 921 - 930.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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