AUSTRAL Biologicals Catalog

Product Sheet: Anti-human Melanoma-Associated Antigen 1 (MAGE-1). IgG fraction (monoclonal)

Catalog NumberMA-721-5
Product IdMA-721-5
Product NameAnti-human Melanoma-Associated Antigen 1 (MAGE-1). IgG fraction (monoclonal)
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryMonoclonal Antibodies (Cancer Antigens)
DescriptionIgG fraction from mouse monoclonal antibody (clone 3H9/F9) obtained by immunization of mice with MAGE-1 protein (48 kDa). The IgG fraction was purified using Protein G-Sepharose.
StorageStore at -20°C.
StabilityStable for at least one year. Avoid repeated freezing and thawing.
Biological ActivityThis antibody can be used for ELISA assay (1:4,000 dilution) and Western Blot (1:2,000 dilution). It recognizes the MAGE-1 protein, a specific antigen that is recognized by autologous cytotoxic T lymphocytes. This cytoplasmatic protein is expressed in melanoma and many malignant tumors, but not in normal tissues except for testes. It may play a role in embryonal development and tumor transformation or aspects of tumor progression.
FormulationSolution at 0.5 mg/mL in PBS
ReferencesChomez, P. et. Al. (2001) Cancer Res. 61, 5544 - 5551.
De Smet, C. (1996) Proc. Natl. Acad. Sci. USA 93, 7149 - 53.
Ding, M. et al (1994) Biochem. Biophys. Res. Commun. 202, 549-
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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