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AUSTRAL Biologicals Catalog

Product Sheet: Anti-human Complement Activation Blocker-2 (CAB-2). IgG fraction (monoclonal)

Catalog NumberMA-1301-5
Product IdMA-1301-5
Product NameAnti-human Complement Activation Blocker-2 (CAB-2). IgG fraction (monoclonal)
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryMonoclonal Antibodies (Growth Factors/Cytokines/Receptors)
DescriptionIgG fraction from mouse monoclonal antibody (clone 4E5/C6) obtained by immunization of mice with human complement activation protein blocker-2, CAB-2 (110 kDa). The IgG fraction was purified using Protein G-Sepharose.
StorageStore at -20°C.
StabilityStable for at least one year. Avoid repeated freezing and thawing.
Biological ActivityThis antibody can be used for ELISA assay (1:2,000 dilution). CAB-2 is a soluble chimeric protein derived from human decay accelerating factor (CD55) and membrane cofactor protein (CD46). It inhibits C3 and C5 convertases of both classical and alternative pathway. It also blocks the activation of complement in vivo.
FormulationSolution at 0.5 mg/mL in PBS
ReferencesHiggins, P.J. et. al. (1997) J. Immunol. 158, 2872 - 2881
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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