AUSTRAL Biologicals Catalog

Product Sheet: Anti-hTNF Receptor-Associated Factor 2 (TRAF 2). IgG faction (monoclonal)

Catalog NumberMR-951-4
Product IdMR-951-4
Product NameAnti-hTNF Receptor-Associated Factor 2 (TRAF 2). IgG faction (monoclonal)
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryMonoclonal Antibodies (Growth Factors/Cytokines/Receptors)
DescriptionIgG fraction from mouse monoclonal antibody (clone 2I10/I5) obtained by immunization of mice with human TRAF2 (50 kDa). The IgG fraction was purified using Protein G-Sepharose.
StorageStore at -20°C.
StabilityStable for at least one year. Avoid repeated freezing and thawing.
Biological ActivityThis antibody can be used for ELISA assay (1:2,000 dilution). TRAF2 is a signal transducer protein that associates with the cytoplasmic domain of TNF receptor to different signaling pathways. It regulates two distinct kinase cascades which lead to NF-?B and JUNK activation. It is also involved in anti-apoptotic signaling, perinatal survival and IL-15 signaling.
FormulationSolution at 1.0 mg/mL in PBS.
ReferencesChung, Y.J. et. al. (2002) J. Cell. Sci. 115, 679 - 688.
Bradley, J.R. & Pober, J. (2001) Oncogene 20, 6482 - 6491.
Wajant, H. et. al. (2001) Cell. Signal. 13, 389 - 400.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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