AUSTRAL Biologicals Catalog

Product Sheet: Anti C-terminal domain of P300/CBP-Associated Factor (human PCAF). IgG fraction (monoclonal)

Catalog NumberTM-701AX-55
Product IdTM-701AX-55
Product NameAnti C-terminal domain of P300/CBP-Associated Factor (human PCAF). IgG fraction (monoclonal)
CategoryProteins and Antibodies for Transcription Research
SubcategoryProteins and Antibodies
DescriptionIgG fraction from mouse monoclonal antibody (clone 7D7/H9) obtained by immunization of mice with the C-terminal domain of human PCAF. The IgG fraction was purified using Protein G-Sepharose.
StorageStore at -20°C.
StabilityStable for at least one year. Avoid repeated freezing and thawing.
Biological ActivityThis antibody can be used for ELISA assay (1:8,000 dilution) and Western Blot. It recognizes the C-terminal domain of PCAF protein. This region of PCAF has intrinsic acetyltransferase activity with core histones (H3 and H4), and with nucleosome core particles to promote transcriptional activation. It also acetylates p53 protein in response to DNA damage.
FormulationSolution at 1.0 mg/mL in PBS.
ReferencesSchiltz, R.L. & Nakatani, Y. (2000) Biochem. Biophys. Acta 1470,
37 - 53.
Liu, L. et. al. (1999) Mol Cell Biol 19, 1202 - 1209.
Yang, X-J. et. al. (1996) Nature 382, 319 - 324.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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