AUSTRAL Biologicals Catalog

Product Sheet: Anti-Cyclin-dependent kinase 8 (CDK 8) IgG fraction (monoclonal)

Catalog NumberTM-381-55
Product IdTM-381-55
Product NameAnti-Cyclin-dependent kinase 8 (CDK 8) IgG fraction (monoclonal)
CategoryProteins and Antibodies for Transcription Research
SubcategoryProteins and Antibodies
DescriptionIgG fraction from mouse monoclonal antibody (clone 9D5/I7) obtained by immunization using a recombinant human CDK8. The IgG fraction was purified using Protein G-Sepharose.
StorageStore at -20°C.
StabilityStable for at least one year. Avoid repeated freezing and thawing.
Biological ActivityThis antibody can be used for ELISA analysis. CDK8 phosphorylates the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II. It is bound to and is activated by Cyclin C. CDK8 is involved in the control of cell cycle by transcriptional regulation.
FormulationSolution at 0.5 mg/mL in PBS (pH 7.2).
ReferencesTassan, J-P. (1995) Proc. Natl. Acad. Sci. USA 92, 8871-8875.
Akoulitchev, S. et al. (2000) Nature 407, 102 – 106.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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