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AUSTRAL Biologicals Catalog

Product Sheet: Anti- human large subunit (68 kDa) of TFIIE-gamma IgG fraction (monoclonal)

Catalog NumberTM-281-55
Product IdTM-281-55
Product NameAnti- human large subunit (68 kDa) of TFIIE-gamma IgG fraction (monoclonal)
CategoryProteins and Antibodies for Transcription Research
SubcategoryProteins and Antibodies
DescriptionIgG fraction from mouse monoclonal antibody (clone 4C2/E7) obtained by immunization using purified human transcription factor IIE-gamma (p68). The IgG fraction was purified using Protein G-Sepharose.
StorageStore at -20°C.
StabilityStable for at least one year. Avoid repeated freezing and thawing.
Biological ActivityThis antibody can be used for ELISA (1: 8000 dilution) and Western blot analysis. It recognizes the large subunit (68 kDa) of TFIIE-gamma complex. This complex recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH.
FormulationSolution at 1.0 mg/mL in PBS (pH 7.2).
ReferencesPeterson, M.G. et al (1991) Nature 354, 369 – 373.
Kuhlman, T.C. et al (1999) Mol. Cell. Biol. 19, 2130 – 2141.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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