AUSTRAL Biologicals Catalog

Product Sheet: Anti- human dimethyl - Histone H4 (K20) IgG fraction (monoclonal)

Catalog NumberTM-451-55
Product IdTM-451-55
Product NameAnti- human dimethyl - Histone H4 (K20) IgG fraction (monoclonal)
CategoryProteins and Antibodies for Transcription Research
SubcategoryProteins and Antibodies
DescriptionIgG fraction from mouse monoclonal antibody (clone 7H8/I5) obtained by immunization using a KLH-conjugated synthetic peptide corresponding to aa17 – aa28 of human Histone H4. The IgG fraction was purified using Protein G-Sepharose.
StorageStore at -20°C.
StabilityStable for at least one year. Avoid repeated freezing and thawing.
Biological ActivityThis antibody can be used in ELISA assays (1: 8,000 dilution), immunoblot, immunohistochemistry and immunoprecipitation analysis. It recognizes Histone H4 dimethylated on lysine 20. This modification is associated with silent, transcriptionally inactive regions within the euchromatin. This antibody is used to study the mechanisms of regulation of chromatin structure during transcription.
FormulationSolution at 1.0 mg/mL in PBS (pH 7.2).
ReferencesNishioka, K et al. (2002) Mol. Cell. 9, 1201 – 1213.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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