AUSTRAL Biologicals Catalog

Product Sheet: Insulin-like Growth Factor (IGF-I) human (RECOMBINANT)

Catalog NumberGF-050-4
Product IdGF-050-4
Product NameInsulin-like Growth Factor (IGF-I) human (RECOMBINANT)
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryGrowth Factors/Cytokines/Enzymes
DescriptionHuman IGF-I is a potent mitogen for mesenchymally-derived cells. It is composed of 70 amino acid residues, and is 62% homologous with human IGF-II. Human IGF-I is produced by genetically engineered yeast, and purified by sequential chromatography.
Mol Weight7.5 KDa
PurityOver 95% pure by N-terminal amino acid sequencing, amino acid composition, HPLC analysis, and SDS gel electrophoresis.
StorageStore at +4°C. Reconstitution is best in water or buffer near neutral pH. After reconstitution, storage in aliquots at -80°C is recommended.
StabilitySeveral months, lyophilized or in solution, at pH 6-7 and +4°C.
Biological ActivityThe material is active in a receptor-binding assay using a membrane preparation from placenta.
FormulationLyophilized powder
References1. Modern Concepts of Insulin-Like Growth Factor. Ed. E. Martin Spencer, M.D. (1991). Elsevier Science Publ. (New York).
2 D'Ercole, A.J. (1987) J. Dev. Physiol. 9:481-495
3. Daughaday, W.H. and Rotwein, P. (1989) Endocr. Rev. 10:68-91
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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