AUSTRAL Biologicals Catalog

Product Sheet: Rabbit anti-Human Upstream Stimulatory Factor 1 (USF1) IgG fraction polyclonal antibody

Catalog NumberTP-2001-9
Product IdTP-2001-9
Product NameRabbit anti-Human Upstream Stimulatory Factor 1 (USF1) IgG fraction polyclonal antibody
CategoryProteins and Antibodies for Transcription Research
SubcategoryPolyclonal Antibodies (Cancer/Transcription Factors)
DescriptionIgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (MKGQQKTAETEEGT) corresponding to amino acids 1-14 of human USF-1. The IgG fraction was purified using Protein G-Sepharose.
Mol WeightN/A
StorageStore at -20ºC.
StabilityStable at least one year at -20ºC. Avoid repeated freezing and thawing.
Biological ActivityThis polyclonal antibody can be used in ELISA (1: 250 dilution), immunocytochemistry (1: 100 dilution) and it recognizes USF-1 (33,5 kDa) in Western blot of HeLa lysate (1: 500 dilution). Upstream stimulatory factor 1 (UFS-1) is a 33.5 kDa nuclear protein that exhibits site-specific DNA binding activating the transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. USF-1 is a member of the basic helix-loop-helix leucine zipper family and can function as a cellular transcription factor.This protein has been associated to familial combined hyperlipidemia.
FormulationSolution at 1 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.
ReferencesSawadogo, M. (1988) J. Biol. Chem. 263, 11994-12001. Gregor, P.D. et al. (1990) Genes Dev. 4, 1730-1740. Pajukanta, P. et al. (2004) Nat. Genet. 36, 371-376.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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