AUSTRAL Biologicals Catalog

Product Sheet: Rabbit anti-Human Heregulin-1 (Neuregulin-1) precursor IgG fraction polyclonal antibody

Catalog NumberPN-7070a-9
Product IdPN-7070a-9
Product NameRabbit anti-Human Heregulin-1 (Neuregulin-1) precursor IgG fraction polyclonal antibody
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryPolyclonal Antibodies (Neurobiology)
DescriptionIgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (AGRFSTQEEIQARLSSVIANQDPIAV) corresponding to amino acids 614 - 639 of human Heregulin-1. The IgG fraction was purified using Protein G-Sepharose.
Mol WeightN/A
StorageStore at -20ºC.
StabilityStable at least one year at -20ºC. Avoid repeated freezing and thawing.
Biological ActivityThis polyclonal antibody reacts in ELISA and Western Blot using the immunizing peptide. Heregulin-1, also known as neu differentiation factor -2 (NDF) or Neuregulin-1(NRG1) plays an important role in regulating cell proliferation, metastasis, differentiation, and survival of varios normal and neoplastic tissues. It binds to c-erbB-3 and c-erbB-4 tyrosine kinase receptors, and has diverse functions in neural development and neuromuscular junctions.
FormulationSolution at 1 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.
ReferencesHolmes, W.E. et al. (1992) Science 256, 1205 - 1210. Falls, D.L. (2003) Exp. Cell. Res. 284, 14 - 30. Esper, R.M. et al. (2006) Brain. Res. Rev. 51, 161 - 175.
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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