| Catalog Number | PN-7020a-9 |
| Product Id | PN-7020a-9 |
| Product Name | Rabbit anti-Human Gamma- Synuclein IgG fraction polyclonal antibody |
| Temperature | -20°C |
| Unit | 1mg |
| Price | 425 |
| Availability | Available |
| Category | Growth Factors, Cytokines, Receptors and their Antibodies |
| Subcategory | Polyclonal Antibodies (Neurobiology) |
| Description | IgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (EKEEVAEEAQSGGD) corresponding to amino acids 114 - 127 of human gamma-synuclein. The IgG fraction was purified using Protein G-Sepharose. |
| Isotype | N/A |
| Mol Weight | N/A |
| Purity | N/A |
| Storage | Store at -20ºC. |
| Stability | Stable at least one year at -20ºC. Avoid repeated freezing and thawing. |
| Biological Activity | This polyclonal antibody reacts in ELISA and Western Blot using the immunizing peptide. Human Gamma-Synuclein (breast cancer-specific gene 1) is a soluble protein belonging to the synuclein family. This protein is expressed in the peripheral nervous system and it is overexpressed in advanced infiltrating breast cancer and other different cancers. Gamma-Synuclein is also associated with axonal pathology in Parkinson's desease and others neurodegenerative disordes. |
| Formulation | Solution at 1 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial. |
| References | Lavedan, C. et al. (1998) Hum. Genet 103 (1), 106 - 112. Clayton, D.F. & George, J.M. (1998) Trends Neurosci. 21 (6), 249 254. George, J.M. (2002) Genome Biol.3, 3002.1 - 3002.6 |
