AUSTRAL Biologicals Catalog

Product Sheet: Rabbit anti-Human Beta- Synuclein IgG fraction polyclonal antibody

Catalog NumberPN-7010a-9
Product IdPN-7010a-9
Product NameRabbit anti-Human Beta- Synuclein IgG fraction polyclonal antibody
CategoryGrowth Factors, Cytokines, Receptors and their Antibodies
SubcategoryPolyclonal Antibodies (Neurobiology)
DescriptionIgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (IEPLMEPEGESYEDPPQE) corresponding to amino acids 108 - 125 of human Beta-Synuclein. The IgG fraction was purified using Protein G-Sepharose.
Mol WeightN/A
StorageStore at -20ºC.
StabilityStable at least one year at -20ºC. Avoid repeated freezing and thawing.
Biological ActivityThis polyclonal antibody reacts in ELISA and Western Blot using the immunizing peptide. Human beta synuclein is a soluble protein highly abundant in presynaptic nerve terminals and a member of the synuclein family. It could act as a physiological negative regulator of Alpha-Synuclein aggregation and it is associated with neurodegenerative disordes.This protein has been shown to be a substrate for phosphorylation by CAM kinase.
FormulationSolution at 1 mg/mL in PBS. Some of the liquid in the vial could have evaporated with changes in the final volume. However, the mass of the protein is still inside the vial.
ReferencesJakes, R. et al. (1994) FEBS Lett 345, 27 - 32. Clayton, D.F. & George, J.M. (1998) Trends Neurosci. 21 (6), 249 254. George, J.M. (2002) Genome Biol.3, 3002.1 - 3002.6. Masliah, E. & Hashimoto, M. (2002) Neurotoxicology 23, 461 - 468
All products are for research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

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